Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 16/20 | 0.44 |
| ▸ | CETP | P11597 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935441 | 0.90 | CACNA1G (0.55) | CACNA1GCACNA1BCACNA1CTACR1CETP | |
| SCHEMBL6678261 | 0.88 | CETP (0.43) | CACNA1GCACNA1BCACNA1CTACR1CETP | |
| SCHEMBL29746466 | 0.85 | CACNA1G (0.51) | CACNA1GCACNA1BCACNA1CTACR1CETP | |
| SCHEMBL13818149 | 0.85 | CACNA1G (0.51) | CACNA1GCACNA1BCACNA1CTACR1CETP | |
| SCHEMBL3005488 | 0.83 | CACNA1G (0.49) | CACNA1GCACNA1BCACNA1CTACR1CETP | |
| SCHEMBL5428175 | 0.82 | TACR1 (0.52) | TACR1 | |
| SCHEMBL10174998 | 0.81 | RIPK1 (0.39) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL25375270 | 0.77 | CACNA1G (0.53) | CACNA1GCACNA1BCACNA1CTACR1CETP | |
| SCHEMBL2228851 | 0.77 | HSD11B1 (0.51) | HTR2CSLC6A4 | |
| SCHEMBL19950236 | 0.76 | CLK1 (0.45) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110687-B2 | Bicyclic compounds with kinase inhibitory activity | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-02-07 | — | — | US | disclosed |