Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | ADCY10 | Q96PN6 | 2/20 | 0.36 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356705 | 0.86 | GPR52 (0.39) | GPR52ADCY10IDH1S1PR1S1PR3 | |
| SCHEMBL29356603 | 0.81 | SCD (0.42) | GPR52CITROCK2PRKCBPRKCA | |
| SCHEMBL29357230 | 0.78 | GPR52 (0.41) | GPR52ROCK2IDH1LMNA | |
| SCHEMBL29356876 | 0.75 | HPGDS (0.38) | GPR52ADCY10IDH1MAOBPARP10 | |
| SCHEMBL29357160 | 0.75 | BRD4 (0.38) | GPR52ADCY10IDH1CASRMAOB | |
| SCHEMBL21395094 | 0.73 | MAPT (0.49) | NTRK1SCDSCD5ALDH1A1ABCC8 | |
| SCHEMBL29358258 | 0.70 | SCD (0.38) | GPR52IDH1MAOBPARP10SCD | |
| SCHEMBL29355412 | 0.69 | AURKA (0.44) | GPR52PRKACAROCK1IDH1PDE4D | |
| SCHEMBL21384289 | 0.68 | ADCY10 (0.42) | GPR52ADCY10 | |
| SCHEMBL29356546 | 0.67 | GAA (0.39) | GPR52ADCY10GAABRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |