Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | ADCY10 | Q96PN6 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354571 | 0.86 | GPR52 (0.38) | GPR52IDH1ALDH1A1HPGDGAA | |
| SCHEMBL29356603 | 0.79 | SCD (0.42) | GPR52IDH1MAOBPARP10LMNA | |
| SCHEMBL29357230 | 0.76 | GPR52 (0.41) | GPR52IDH1BTKLMNA | |
| SCHEMBL21394964 | 0.74 | MAPT (0.46) | RIPK1ALDH1A1GAARECQLKDM4E | |
| SCHEMBL29356876 | 0.73 | HPGDS (0.38) | GPR52IDH1MAOBPARP10ADCY10 | |
| SCHEMBL29357160 | 0.73 | BRD4 (0.38) | GPR52IDH1CASRMAOBPARP10 | |
| SCHEMBL21383966 | 0.70 | DRD2 (0.40) | GPR52ADORA2AKDM4E | |
| SCHEMBL29358258 | 0.68 | SCD (0.38) | GPR52IDH1PKMMAOBPARP10 | |
| SCHEMBL29358556 | 0.67 | IDH1 (0.40) | GPR52RIPK1IDH1 | |
| SCHEMBL29355412 | 0.67 | AURKA (0.44) | GPR52IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |