Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27739908 | 1.00 | LMNA (0.47) | LMNAALDH1A1MAPTPTGS2TDP1 | |
| SCHEMBL27739903 | 1.00 | LMNA (0.47) | LMNAALDH1A1MAPTPTGS2TDP1 | |
| SCHEMBL29980033 | 0.92 | LMNA (0.43) | LMNAALDH1A1MAPTPTGS2TDP1 | |
| SCHEMBL30569806 | 0.91 | ALDH1A1 (0.42) | LMNAALDH1A1MAPTPTGS2TDP1 | |
| SCHEMBL29566626 | 0.88 | ALDH1A1 (0.46) | LMNAALDH1A1MAPTPTGS2TDP1 | |
| SCHEMBL7200312 | 0.86 | KMT2A (0.38) | LMNAECE1CTSCCTSSCTSK | |
| SCHEMBL7200310 | 0.86 | KMT2A (0.38) | LMNAECE1CTSCCTSSCTSK | |
| SCHEMBL22892432 | 0.85 | MME (0.53) | LMNAALDH1A1MAPTPTGS2TDP1 | |
| SCHEMBL22892480 | 0.85 | MME (0.53) | LMNAALDH1A1MAPTPTGS2TDP1 | |
| SCHEMBL28706003 | 0.85 | MME (0.53) | LMNAALDH1A1MAPTPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017541-A1 | IMMUNE TOLERANT ELASTIN-LIKE RECOMBINANT PEPTIDES AND METHODS OF USE | University of Utah Research Foundation (US) | 2022-06-29 | — | — | EP | claimed |
| US-12622975-B2 | Peptide-conjugated prodrugs | BRANDEIS UNIVERSITY (US) | 2026-05-12 | — | — | US | disclosed |
| CN-118792318-A | Application of nucleic acid molecule and OsCTS protein coded by same in regulation and control of rice seedling stage cold resistance | 中国农业大学 | 2024-10-18 | — | — | CN | disclosed |
| WO-2023064887-A1 | MECHANOCHEMICAL DYNAMIC THERAPY FOR FOCAL CANCER TREATMENT | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-04-20 | — | — | WO | disclosed |
| US-20230109312-A1 | NOVEL LINKERS FOR ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | IGENICA BIOTHERAPEUTICS, INC. | 2023-04-06 | — | — | US | disclosed |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-12-08 | — | — | US | disclosed |
| US-11229711-B2 | Linkers for antibody-drug conjugates and related compounds, compositions, and methods of use | Magenta Therapeutics, Inc. (US) | 2022-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622975-B2 | Peptide-conjugated prodrugs | PEPD, PAM, VIP | LMNA 1538/4885ALDH1A1 3596/4885MAPT 3330/4885 |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | VIP, DNPEP, PEPD | LMNA 3184/4885ALDH1A1 4110/4885MAPT 4191/4885 |
| US-20230109312-A1 | NOVEL LINKERS FOR ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SDCBP, DCLRE1A, BCR | LMNA 1207/4885ALDH1A1 2431/4885MAPT 1441/4885 |
| US-11229711-B2 | Linkers for antibody-drug conjugates and related compounds, compositions, and methods of use | CLSPN, SDCBP, DCLRE1A | LMNA 832/4885ALDH1A1 2503/4885MAPT 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.