SCHEMBL29355207

SCHEMBL29355207

CC(=O)Cc1ncc(Cl)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.42
LMNA P02545 2/20 0.42
TDP1 Q9NUW8 4/20 0.39
PLAU P00749 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
PTK2 Q05397 1/20 0.36
NR4A1 P22736 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
POLB P06746 2/20 0.35
MAPT P10636 2/20 0.35
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
APEX1 P27695 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
AGBL2 Q5U5Z8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22530354 1.00 L3MBTL1 (0.42) L3MBTL1LMNATDP1PLAUCYP1A2
SCHEMBL15999660 0.84 CYP1A2 (0.39) CYP1A2CYP3A4CYP2D6CYP2C19MEN1
SCHEMBL29354953 0.83 LMNA (0.51) L3MBTL1LMNATDP1PLAUNR4A1
SCHEMBL940173 0.83 LMNA (0.51) L3MBTL1LMNATDP1PLAUNR4A1
SCHEMBL10132016 0.78 DPP4 (0.44) L3MBTL1TDP1NR4A1POLBMAPT
SCHEMBL14920934 0.78 CYP1A2 (0.58) L3MBTL1TDP1CYP1A2CYP3A4CYP2D6
SCHEMBL990259 0.74 PLAU (0.47) L3MBTL1LMNATDP1PLAUCYP3A4
SCHEMBL10264617 0.74 CRHR1 (0.46) L3MBTL1LMNATDP1PLAUMEN1
SCHEMBL12085878 0.74 L3MBTL1 (0.37) L3MBTL1LMNATDP1PLAUNR4A1
SCHEMBL14984459 0.73 L3MBTL1 (0.41) L3MBTL1LMNATDP1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3952652-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2022-02-16 EP disclosed
CN-113966171-A Fungicidal compositions 先正达农作物保护股份公司 2022-01-21 CN disclosed