Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27716277 | 0.86 | AGBL2 (0.69) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL1855724 | 0.85 | MAPT (0.60) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL784677 | 0.85 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL3422410 | 0.84 | HTT (0.57) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL20972172 | 0.84 | LMNA (0.61) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| Acetic Acid SCHEMBL5046683 | 0.82 | KMT2A (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL4654059 | 0.82 | TDP1 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL4376390 | 0.81 | L3MBTL1 (0.64) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| Acetic Acid SCHEMBL28417972 | 0.81 | KMT2A (0.54) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| Acetic Acid SCHEMBL4444086 | 0.80 | KMT2A (0.53) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9301526-B2 | Compounds with nematicidal activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-9301526-B2 | Compounds with nematicidal activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| EP-2773215-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | Bayer Intellectual Property GmbH (DE) | 2014-09-10 | — | — | EP | disclosed |
| EP-2773203-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | Bayer Intellectual Property GmbH (DE) | 2014-09-10 | — | — | EP | disclosed |
| US-20140249149-A1 | Compounds with Nematicidal Activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| US-20140249149-A1 | Compounds with Nematicidal Activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| EP-2606728-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-06-26 | — | — | EP | disclosed |
| EP-2606728-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-06-26 | — | — | EP | disclosed |
| EP-2606727-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-06-26 | — | — | EP | disclosed |
| EP-2606727-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-06-26 | — | — | EP | disclosed |
| WO-2013064461-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064461-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064460-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064460-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | ACHE, TUBA3C, NAAA | CYP1A2 714/4885CYP3A4 852/4885CYP2D6 1494/4885 |
| US-20140249149-A1 | Compounds with Nematicidal Activity | ACHE, NAAA, TUBA3C | CYP1A2 947/4885CYP3A4 874/4885CYP2D6 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.