SCHEMBL9514064

SCHEMBL9514064

CC(C)(C)c1cccc(Cc2ccccc2)c1O

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.55
GABRA1 P14867 2/20 0.53
GABRB2 P47870 2/20 0.53
ATM Q13315 1/20 0.47
BCL2 P10415 1/20 0.46
BCL2L1 Q07817 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HSPA5 P11021 1/20 0.42
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10495890 0.88 CA2 (0.53) CA2GABRA1GABRB2ATMNPSR1
SCHEMBL2935552 0.87 CA2 (0.67) CA2GABRA1GABRB2ATMNPSR1
SCHEMBL27685494 0.86 GABRA1 (0.55) CA2GABRA1GABRB2ATMNPSR1
SCHEMBL9679932 0.85 PTPN1 (0.51) CA2GABRA1GABRB2NPSR1ALDH1A1
SCHEMBL9817051 0.84 CA2 (0.59) CA2GABRA1GABRB2ATMNPSR1
SCHEMBL6546758 0.83 CALM1 (0.46) BCL2BCL2L1ALDH1A1TSHRTDP1
SCHEMBL23842558 0.82 GABRA1 (0.69) CA2GABRA1GABRB2ATMNPSR1
SCHEMBL9861938 0.82 BCL2 (0.46) ATMBCL2BCL2L1ALDH1A1
SCHEMBL9752003 0.82 HSPA5 (0.57) CA2GABRA1GABRB2ATMNPSR1
SCHEMBL4966037 0.80 BCL2 (0.60) BCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103201109-B Gas-barrier film, process for producing same, member for electronic device, and electronic device LINTEC CORP. (JP) 2014-10-22 CN disclosed
CN-104066576-A Gas barrier film, method for producing same, gas barrier film laminate, member for electronic device, and electronic device LINTEC CORP 2014-09-24 CN disclosed
CN-103974981-A Curable resin composition, curable resin molded body, cured resin molded body, method for producing each of same, and laminate body LINTEC CORP 2014-08-06 CN disclosed
CN-103201109-A Gas-barrier film, process for producing same, member for electronic device, and electronic device LINTEC CORP 2013-07-10 CN disclosed
EP-0213788-B1 Method for improving the clarity of propylene polymers REXENE PROD CO (US) 1993-11-03 EP disclosed
US-4877902-A REACTING 2,6-DIALKYLPHENOL WITH SULFUR CHLORIDE AT LOW TEMPERATURE ETHYL CORPORATION (US) 1989-10-31 US disclosed
EP-0213788-A2 Method for improving the clarity of propylene polymers REXENE PRODUCTS COMPANY (A Delaware Corporation) (US) 1987-03-11 EP disclosed