Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57139 | 0.85 | GABRA1 (0.67) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL2935552 | 0.85 | CA2 (0.67) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL3809080 | 0.84 | CA2 (0.59) | CA2GABRA1GABRB2ATMALOX12 | |
| Propane SCHEMBL28225674 | 0.83 | GABRA1 (0.64) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL358963 | 0.82 | ALDH1A1 (0.52) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL29747171 | 0.82 | ALDH1A1 (0.52) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL9994746 | 0.82 | CA2 (0.61) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL1274723 | 0.82 | CA2 (0.61) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL27555820 | 0.82 | CA2 (0.61) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL3510896 | 0.82 | CA2 (0.61) | CA2GABRA1GABRB2ATMALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106169-B1 | SUBSTITUTED 2-(2,6-DI-T-BUTYL-4-ALKYLPHENOXY) 4H-1,3,2-BENZODIOXAPHOSPHORINS AND COMPOSITIONS THEREOF | The B.F. GOODRICH Company (US) | 1988-01-07 | — | — | EP | disclosed |
| US-4529533-A | Substituted 2-(2,6-di-t-butly-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0106169-A1 | Substituted 2-(2,6-di-t-butyl-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof | The B.F. GOODRICH Company (US) | 1984-04-25 | — | — | EP | disclosed |
| US-4439564-A | 5-Membered cyclic phosphonates and compositions thereof | THE B. F. GOODRICH CO. (US) | 1984-03-27 | — | — | US | disclosed |