Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655832 | 0.73 | L3MBTL1 (0.56) | TSHRRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL3778015 | 0.72 | TSHR (0.68) | TSHRRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL994563 | 0.69 | RAB9A (0.55) | TSHRRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5746819 | 0.68 | RAB9A (0.58) | TSHRRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL2654505 | 0.67 | L3MBTL1 (0.59) | TSHRRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL29353713 | 0.67 | SMN1; SMN2 (0.64) | TSHRRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL29937254 | 0.66 | ALDH1A1 (0.55) | TSHRRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL10809546 | 0.66 | L3MBTL1 (1.00) | TSHRRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL2906397 | 0.65 | RAB9A (0.51) | TSHRRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL6675218 | 0.65 | TSHR (0.56) | TSHRRAB9ASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |