SCHEMBL29357401

SCHEMBL29357401

CC(C)[C@H](N)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ APC P25054 3/20 0.58
▸ BACE1 P56817 3/20 0.53
▸ QRFPR Q96P65 2/20 0.51
▸ KEAP1 Q14145 1/20 0.50
▸ PTPN1 P18031 1/20 0.49
▸ OPRD1 P41143 2/20 0.49
▸ OPRM1 P35372 1/20 0.49
▸ OPRK1 P41145 1/20 0.49
▸ CCKBR P32239 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30570452 0.83 OPRL1 (0.50) BACE1QRFPROPRD1OPRM1OPRK1
SCHEMBL29939679 0.83 APC (0.55) APCBACE1QRFPRKEAP1OPRD1
SCHEMBL29512270 0.83 APC (0.55) APCBACE1QRFPRKEAP1OPRD1
SCHEMBL31256956 0.82 OPRD1 (0.57) APCBACE1OPRD1OPRM1OPRK1
SCHEMBL29670260 0.82 TFPI (0.56) APCBACE1QRFPR
SCHEMBL30643193 0.81 OPRM1 (0.58) APCBACE1KEAP1PTPN1OPRD1
SCHEMBL30445627 0.81 OPRM1 (0.54) OPRD1OPRM1OPRK1
SCHEMBL31005067 0.81 BACE1 (0.70) BACE1
SCHEMBL30312239 0.80 BACE1 (0.57) BACE1
SCHEMBL2735762 0.79 APC (0.52) APCQRFPRKEAP1PTPN1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133111-A1 CGRP RECEPTOR AGONISTS IN ISCHEMIC HEART DISEASE EPOQE PHARMA APS (DK) 2025-06-26 — — WO claimed
EP-2964658-B1 POSITRON-EMITTING SUBSTITUTED ORGANOFLUOROBORATES AS IMAGING AGENTS UNIV BRITISH COLUMBIA (CA) 2024-08-07 — — EP claimed
CN-114099775-A HAp-SF artificial periosteum loading SDF-1 alpha/CGRP and preparation method thereof 华南理工大学 2022-03-01 — — CN claimed
EP-4748439-A2 A PEPTOID-PEPTIDE HYBRID, NMEG-ALPHA-CGRP, AND ITS USE IN CARDIOVASCULAR DISEASES University of South Carolina (US) 2026-05-27 — — EP disclosed
EP-3609434-B1 MEDICAL DEVICES COATED WITH POLYDOPAMINE AND ANTIBODIES ORBUSNEICH MEDICAL PTE LTD (SG) 2026-05-20 — — EP disclosed
EP-4705339-A1 COMPOSITION, METHODS AND USES 4E Therapeutics, Inc. (US) 2026-03-11 — — EP disclosed
CN-121426953-A Preparation method of CGRP detection kit and application of CGRP detection kit in migraine diagnosis 江苏美克医学技术有限公司 2026-01-30 — — CN disclosed
EP-3970725-B1 A GAMMA SECRETASE INHIBITOR FOR TREATING HEARING LOSS MASSACHUSETTS EYE & EAR INFIRMARY (US) 2025-08-20 — — EP disclosed
WO-2025133111-A1 CGRP RECEPTOR AGONISTS IN ISCHEMIC HEART DISEASE EPOQE PHARMA APS (DK) 2025-06-26 — — WO disclosed
US-20250186595-A1 A CONJUGATE CONSISTING OF OR COMPRISING AT LEAST A ß-GLUCAN OR A MANNAN TRIDEM BIOSCIENCE GMBH & CO KG (AT) 2025-06-12 — — US disclosed
US-20250186580-A1 A CONJUGATE COMPRISING AT LEAST A ß-GLUCAN TRIDEM BIOSCIENCE GMBH & CO KG (AT) 2025-06-12 — — US disclosed
CN-114245798-A CGRP antagonist compounds 赫普泰雅治疗有限公司 2022-03-25 — — CN disclosed
CN-108025044-B Immunogenic procalcitonin precursor peptides 古斯塔夫鲁西研究院 2022-03-25 — — CN disclosed
EP-3970725-A1 A GAMMA SECRETASE INHIBITOR FOR TREATING HEARING LOSS Massachusetts Eye & Ear Infirmary (US) 2022-03-23 — — EP disclosed
EP-3165236-B1 METHODS FOR TREATING VISCERAL PAIN BY ADMINISTERING ANTAGONIST ANTIBODIES DIRECTED AGAINST CALCITONIN GENE-RELATED PEPTIDE TEVA PHARMACEUTICALS INT GMBH (CH) 2022-03-16 — — EP disclosed
CN-114099775-A HAp-SF artificial periosteum loading SDF-1 alpha/CGRP and preparation method thereof 华南理工大学 2022-03-01 — — CN disclosed
CN-114099775-A HAp-SF artificial periosteum loading SDF-1 alpha/CGRP and preparation method thereof 华南理工大学 2022-03-01 — — CN disclosed
CN-114099775-A HAp-SF artificial periosteum loading SDF-1 alpha/CGRP and preparation method thereof 华南理工大学 2022-03-01 — — CN disclosed
EP-3016684-B1 REGULATION OF GLUCOSE METABOLISM USING ANTI-CGRP ANTIBODIES H LUNDBECK AS (DK) 2022-02-23 — — EP disclosed
US-11254932-B2 Conditionally active biological proteins BIOATLA, INC. (US) 2022-02-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186595-A1 A CONJUGATE CONSISTING OF OR COMPRISING AT LEAST A ß-GLUCAN OR A MANNAN CD4, CD74, CD47 APC 2038/4885BACE1 769/4885QRFPR 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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