Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 7/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5786488 | 0.82 | RAB9A (0.43) | L3MBTL1RAB9ACYP3A4 | |
| SCHEMBL29357073 | 0.77 | RPS6KB1 (0.45) | RPS6KB1L3MBTL1PLA2G1BATG4BCYP11B1 | |
| SCHEMBL29355505 | 0.75 | RPS6KB1 (0.43) | RPS6KB1L3MBTL1PLA2G1BATG4BCYP11B1 | |
| SCHEMBL29358907 | 0.74 | RPS6KB1 (0.42) | RPS6KB1CYP11B1CYP11B2AKT1GPR52 | |
| SCHEMBL29358387 | 0.70 | HPGDS (0.41) | RPS6KB1CYP11B1CYP11B2BRS3AKT1 | |
| SCHEMBL29355501 | 0.70 | GPR52 (0.41) | RPS6KB1L3MBTL1PLA2G1BATG4BCYP11B1 | |
| SCHEMBL29355361 | 0.69 | GPR52 (0.40) | CYP11B1CYP11B2BRS3GPR52CYP3A4 | |
| SCHEMBL29356932 | 0.69 | PLA2G1B (0.41) | RPS6KB1L3MBTL1PLA2G1BATG4BCYP11B1 | |
| SCHEMBL27964788 | 0.68 | RORB (0.68) | RPS6KB1RORBRAB9APDE4D | |
| SCHEMBL29359158 | 0.68 | HPGDS (0.43) | RPS6KB1CYP11B1CYP11B2BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |