SCHEMBL29358995

SCHEMBL29358995

CO/C=C(\Oc1cc(Br)ccc1C)C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.36
MAPT P10636 4/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
PKM P14618 1/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP3A4 P08684 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 3/20 0.35
CYP2C9 P11712 1/20 0.35
KDM4E B2RXH2 3/20 0.34
RXFP1 Q9HBX9 1/20 0.34
ACHE P22303 1/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 2/20 0.34
MEN1 O00255 1/20 0.34
NCEH1 Q6PIU2 1/20 0.33
HPGD P15428 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22488405 1.00 SMN1; SMN2 (0.36) SMN1; SMN2MAPTNPC1RAB9APKM
SCHEMBL21647861 0.87 SMN1; SMN2 (0.37) SMN1; SMN2MAPTNPC1RAB9APKM
SCHEMBL21858354 0.87 SMN1; SMN2 (0.37) SMN1; SMN2MAPTNPC1RAB9APKM
SCHEMBL29877605 0.87 SMN1; SMN2 (0.37) SMN1; SMN2MAPTNPC1RAB9APKM
SCHEMBL29501994 0.84 HPGD (0.40) SMN1; SMN2MAPTNPC1RAB9ACYP1A2
SCHEMBL26418733 0.84 APP (0.38) SMN1; SMN2MAPTCYP1A2CYP2C19ALDH1A1
SCHEMBL23712620 0.83 ALDH1A1 (0.42) SMN1; SMN2MAPTCYP1A2CYP2C19CYP3A4
SCHEMBL30417256 0.83 ACHE (0.34) SMN1; SMN2MAPTKDM4EACHEKMT2A
SCHEMBL7801834 0.83 POLB (0.44) SMN1; SMN2MAPTCYP1A2CYP2C19NPSR1
SCHEMBL7801833 0.83 POLB (0.44) SMN1; SMN2MAPTCYP1A2CYP2C19NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094943-A Novel 1,2, 4-oxadiazoles as fungicides 2026-05-26 CN disclosed
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP disclosed
US-12532884-B2 Fungicidal compositions SYNGENTA CROP PROTECTION AG (CH) 2026-01-27 US disclosed
US-12520843-B2 Plant disease control composition and plant disease control method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-01-13 US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 US disclosed
US-12336537-B2 Fungicidal compositions SYNGENTA CROP PROTECTION AG (CH) 2025-06-24 US disclosed
US-12262710-B2 Fungicidal compounds SYNGENTA CROP PROTECTION AG (CH) 2025-04-01 US disclosed
WO-2025052333-A1 NOVEL 1,2,4-OXADIAZOLES COMPOUNDS AS FUNGICIDE PI INDUSTRIES LTD. (IN) 2025-03-13 WO disclosed
US-20240389582-A1 ACRYLATE DERIVATIVE, USE AND PRODUCTION INTERMEDIATE COMPOUND OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-11-28 US disclosed
US-20240389583-A1 ACRYLATE DERIVATIVE, USE AND PRODUCTION INTERMEDIATE COMPOUND OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-11-28 US disclosed
CN-115697063-A Fungicidal compositions 先正达农作物保护股份公司 2023-02-03 CN disclosed
EP-4114184-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2023-01-11 EP disclosed
EP-4114183-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2023-01-11 EP disclosed
CN-115209735-A Fungicidal compositions 先正达农作物保护股份公司 2022-10-18 CN disclosed
CN-115209736-A Fungicidal compositions 先正达农作物保护股份公司 2022-10-18 CN disclosed
US-20220256844-A1 ACRYLATE DERIVATIVE, USE AND PRODUCTION INTERMEDIATE COMPOUND OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-08-18 US disclosed
US-20220240504-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-08-04 US disclosed
EP-3992178-A1 ACRYLIC ESTER DERIVATIVE, AND APPLICATION AND PRODUCTION INTERMEDIATE THEREOF Sumitomo Chemical Company, Limited (JP) 2022-05-04 EP disclosed
CN-114026060-A Acrylate derivative, use thereof, and intermediate for production thereof 住友化学株式会社 2022-02-08 CN disclosed
EP-3941898-A1 FUNGICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240389583-A1 ACRYLATE DERIVATIVE, USE AND PRODUCTION INTERMEDIATE COMPOUND OF THE SAME C1S, ACR, AKR1C3 SMN1; SMN2 2971/4885MAPT 3614/4885NPC1 706/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 SMN1; SMN2 1500/4885MAPT 3711/4885NPC1 995/4885
US-20220240504-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 SMN1; SMN2 1500/4885MAPT 3711/4885NPC1 995/4885
US-12532884-B2 Fungicidal compositions CYP4F3, CYP4X1, CYP4B1 SMN1; SMN2 4626/4885MAPT 3116/4885NPC1 4619/4885
US-20220256844-A1 ACRYLATE DERIVATIVE, USE AND PRODUCTION INTERMEDIATE COMPOUND OF THE SAME C1S, ACR, AKR1C3 SMN1; SMN2 2971/4885MAPT 3614/4885NPC1 706/4885
US-20240389582-A1 ACRYLATE DERIVATIVE, USE AND PRODUCTION INTERMEDIATE COMPOUND OF THE SAME C1S, ACR, AKR1C3 SMN1; SMN2 2971/4885MAPT 3614/4885NPC1 706/4885
US-12336537-B2 Fungicidal compositions CYP51A1, CYP4X1, CYP1B1 SMN1; SMN2 3972/4885MAPT 2069/4885NPC1 2486/4885
US-12262710-B2 Fungicidal compounds CYP1B1, CYP51A1, CYP1A1 SMN1; SMN2 1500/4885MAPT 3711/4885NPC1 995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.