SCHEMBL26418733

SCHEMBL26418733

CO/C=C(\Oc1cc(O)ccc1C)C(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
PDK2 Q15119 1/20 0.38
PDK4 Q16654 1/20 0.38
MAOB P27338 3/20 0.37
CAPN1 P07384 1/20 0.37
PARP1 P09874 1/20 0.37
MAOA P21397 1/20 0.37
BACE1 P56817 1/20 0.35
ACHE P22303 1/20 0.35
CHRNA7 P36544 1/20 0.34
TYR P14679 1/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358995 0.84 SMN1; SMN2 (0.36) ACHEALDH1A1MAPTMEN1KMT2A
SCHEMBL30417256 0.84 ACHE (0.34) ACHEMAPTMEN1KMT2AKDM4E
SCHEMBL23712620 0.84 ALDH1A1 (0.42) ACHEALDH1A1MAPTMEN1KMT2A
SCHEMBL22488405 0.84 SMN1; SMN2 (0.36) ACHEALDH1A1MAPTMEN1KMT2A
SCHEMBL8026645 0.83 NOTUM (0.40) ACHEALDH1A1MAPTMEN1KMT2A
SCHEMBL8026643 0.83 NOTUM (0.40) ACHEALDH1A1MAPTMEN1KMT2A
SCHEMBL21675873 0.83 ALDH1A1 (0.42) ALDH1A1MAPTKMT2AKDM4ECYP1A2
SCHEMBL21858304 0.82 ACHE (0.33) CA1CA2ACHEMAPTMEN1
SCHEMBL22855352 0.82 ACHE (0.33) ACHEALDH1A1MAPTMEN1KMT2A
SCHEMBL23712445 0.82 CYP4F2 (0.40) CA12CA2CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127143-A1 METHOD FOR CONTROLLING PHAKOPSORA PACHYRHIZI HAVING RESISTANCE AGAINST QoI FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127143-A1 METHOD FOR CONTROLLING PHAKOPSORA PACHYRHIZI HAVING RESISTANCE AGAINST QoI FUNGICIDE CYC1, COX5B, SQOR APP 1167/4885CA12 3869/4885CA1 3717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.