Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27654149 | 0.91 | ALDH1A1 (0.41) | PPM1BPTPN1PPP1CCALDH1A1HPGD | |
| SCHEMBL15345969 | 0.78 | MMP2 (0.34) | PPM1BPTPN1PPP1CC | |
| SCHEMBL2934643 | 0.78 | MMP2 (0.34) | PPM1BPTPN1PPP1CC | |
| SCHEMBL29239191 | 0.74 | MAPK1 (0.32) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28439815 | 0.72 | PPM1B (0.54) | PPM1BPTPN1PPP1CCNPC1ALDH1A1 | |
| SCHEMBL10857235 | 0.72 | MAPK1 (0.34) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10857230 | 0.72 | MAPK1 (0.34) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17361182 | 0.70 | ALDH1A1 (0.52) | PPM1BPTPN1PPP1CCNPC1ALDH1A1 | |
| SCHEMBL17904756 | 0.70 | LMNA (0.40) | PPM1BPTPN1PPP1CCALDH1A1HSD17B10 | |
| SCHEMBL13085057 | 0.70 | LMNA (0.40) | PPM1BPTPN1PPP1CCALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |