Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 13/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 13/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 13/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 13/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.81 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.81 |
| ▸ | PRKACA | P17612 | 1/20 | 0.70 |
| ▸ | PRKACG | P22612 | 1/20 | 0.70 |
| ▸ | PRKACB | P22694 | 1/20 | 0.70 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2713659 | 1.00 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL29384358 | 1.00 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL5951342 | 1.00 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL13300468 | 1.00 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL16079734 | 1.00 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL9702440 | 0.90 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL13300472 | 0.90 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL15906331 | 0.90 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL29381703 | 0.90 | RAPGEF3 (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL1106661 | 0.90 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122038274-A | Method for inducing differentiation and maturation of alveolar organoids and application thereof | 广州国家实验室 | 2026-05-15 | — | — | CN | claimed |
| US-20260125650-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES | TRAILHEAD BIOSYSTEMS INC (US) | 2026-05-07 | — | — | US | claimed |
| EP-4680726-A2 | STEM CELL AND ORGANOID BASED METHODS FOR DIAGNOSTICS AND OPTIMIZATION OF EMBRYO IMPLANTATION | Simbryo Technologies, Inc. (US) | 2026-01-21 | — | — | EP | claimed |
| US-20250304916-A1 | METHODS AND COMPOSITIONS FOR GENERATING VASCULAR LEPTOMENINGEAL CELLS | TRAILHEAD BIOSYSTEMS INC (US) | 2025-10-02 | — | — | US | claimed |
| EP-4605517-A1 | AN IN VITRO METHOD FOR PRODUCING A 3D-STRUCTURE OF CELLS | Universiteit Maastricht (NL) | 2025-08-27 | — | — | EP | claimed |
| US-20250263669-A1 | INDUCED TOTIPOTENT STEM CELLS AND PREPARATION METHOD THEREFOR | UNIV TSINGHUA (CN) | 2025-08-21 | — | — | US | claimed |
| CN-120192914-A | Blood sinus networked liver organoid construction method and application | 淇嘉科技(苏州)有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-119875992-A | Culture system for generating alveolar organoids with alveolar sac morphology based on adult lung stem cells and application of culture system | 中国医学科学院生物医学工程研究所 | 2025-04-25 | — | — | CN | claimed |
| CN-119875991-A | Lung airway organoid culture system with tracheal branch morphological structure, application thereof and culture method | 中国医学科学院生物医学工程研究所 | 2025-04-25 | — | — | CN | claimed |
| EP-4536806-A2 | GENERATION OF LUNG ORGANOIDS FROM PLURIPOTENT STEM CELLS AND USE THEREOF | The Trustees Of Columbia University In The City Of New York (US) | 2025-04-16 | — | — | EP | claimed |
| CN-114181893-B | Method for maturing liver double-phenotype cell | 天津外泌体科技有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-111004770-B | Functional hepatocyte induction method and special three-dimensional induction culture medium and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-08-23 | — | — | CN | claimed |
| WO-2022168908-A1 | PRODUCTION METHOD FOR INTESTINAL TRACT CELLS DERIVED FROM PLURIPOTENT STEM CELLS AND HAVING CRYPT-VILLUS-LIKE STRUCTURES, AND USE THEREOF | 公立大学法人名古屋市立大学 | 2022-08-11 | — | — | WO | claimed |
| US-20220186189-A1 | METHOD FOR INDUCING DIFFERENTIATION OF ALVEOLAR EPITHELIAL CELLS | KYOTO UNIVERSITY (JP) | 2022-06-16 | — | — | US | claimed |
| WO-2022114937-A1 | DECM EXTRACTED FROM HUMAN LUNG TISSUE AND LUNG ORGANOID CONSTRUCTION METHOD USING SAME | 가톨릭대학교 산학협력단 | 2022-06-02 | — | — | WO | claimed |
| CN-114149961-B | Multi-lineage liver organoid and construction method and application thereof | 天九再生医学(天津)科技有限公司 | 2022-04-22 | — | — | CN | claimed |
| US-11299712-B2 | Method for inducing differentiation of alveolar epithelial cells | KYOTO UNIVERSITY (JP) | 2022-04-12 | — | — | US | claimed |
| CN-114181893-A | Method for maturing liver double-phenotype cell | 天九再生医学(天津)科技有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-114149961-A | Multi-lineage liver organoid and construction method and application thereof | 天九再生医学(天津)科技有限公司 | 2022-03-08 | — | — | CN | claimed |
| US-20220025324-A1 | METHODS OF PRODUCING VENOUS ANGIOBLASTS AND SINUSOIDAL ENDOTHELIAL CELL-LIKE CELLS AND COMPOSITIONS THEREOF | UNIVERSITY HEALTH NETWORK (CA) | 2022-01-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125650-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES | WNT3A, GSK3B, GSK3A | PDE4A 1415/4885PDE4B 1268/4885PDE4C 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.