Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | CA11 | O75493 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24522321 | 1.00 | KDM4E (0.51) | KDM4ECRHBPCRHR2KIF11DDR1 | |
| SCHEMBL22898919 | 0.83 | KDM4E (0.51) | KDM4ECRHBPCRHR2KIF11DDR1 | |
| SCHEMBL20138843 | 0.81 | ALDH1A1 (0.56) | KDM4EMAPTKMT2AGAACCNB2 | |
| SCHEMBL29361281 | 0.81 | ALDH1A1 (0.56) | KDM4EMAPTKMT2AGAACCNB2 | |
| SCHEMBL29799131 | 0.76 | KIF11 (0.66) | KDM4ECRHBPCRHR2KIF11CCNT1 | |
| SCHEMBL24522320 | 0.75 | KDM4E (0.44) | KDM4EKIF11MAPTKMT2AGAA | |
| SCHEMBL29363428 | 0.75 | LMNA (0.51) | KDM4EMAPTKMT2AGAACA9 | |
| SCHEMBL22898794 | 0.75 | LMNA (0.51) | KDM4EMAPTKMT2AGAACA9 | |
| SCHEMBL16920112 | 0.72 | PIM1 (0.46) | CDK9MAPTKMT2AMETCYP2C9 | |
| SCHEMBL24522294 | 0.72 | KDM4E (0.46) | KDM4EKIF11MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206857-B | Benzofuranyl N-acylhydrazone derivatives and pharmaceutical compositions comprising the same | 韩国生命工学研究院 | 2024-09-06 | — | — | CN | disclosed |
| CN-116157120-A | Anti-inflammatory compositions comprising benzofuranyl N-acylhydrazone derivatives | 韩国生命工学研究院 | 2023-05-23 | — | — | CN | disclosed |
| CN-114206857-A | Benzofuranyl N-acylhydrazone derivatives and pharmaceutical compositions containing the same | 韩国生命工学研究院 | 2022-03-18 | — | — | CN | disclosed |
| WO-2022019663-A1 | ANTI-INFLAMMATORY COMPOSITION COMPRISING BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVES | 한국생명공학연구원 | 2022-01-27 | — | — | WO | disclosed |