Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 12/20 | 0.60 |
| ▸ | HTR1B | P28222 | 12/20 | 0.60 |
| ▸ | MPO | P05164 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4791616 | 0.80 | SLC6A4 (0.55) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL8686765 | 0.76 | HTR1D (1.00) | HTR1DHTR1BMPOHTR2ABRD4 | |
| SCHEMBL8903385 | 0.75 | HTR1D (0.98) | HTR1DHTR1BMPOHTR2ABRD4 | |
| SCHEMBL2934047 | 0.72 | MPO (0.71) | HTR1DHTR1BMPOHTR2ABRD4 | |
| SCHEMBL27095364 | 0.72 | HTR7 (0.71) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL26989598 | 0.71 | HTR7 (0.70) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL733997 | 0.69 | MPO (1.00) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL8506914 | 0.69 | HTR1D (0.71) | HTR1DHTR1BMPOHTR2ABRD4 | |
| SCHEMBL2933511 | 0.69 | HTR1A (0.75) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL26508359 | 0.69 | HTR7 (0.71) | HTR1DHTR1BMPOHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220075-A1 | INDOLE COMPOUNDS AND METHODS FOR TREATING VISCERAL PAIN | Neuraxon, INC. (CA) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009062319-A1 | INDOLE COMPOUNDS AND METHODS FOR TREATING VISCERAL PAIN | NEURAXON, INC. (CA) | 2009-05-22 | — | — | WO | disclosed |