Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25243805 | 1.00 | TBK1 (0.49) | TBK1GPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL25278423 | 0.81 | GPR119 (0.50) | TBK1GPR119PIK3CDALOX5APFEN1 | |
| SCHEMBL29364064 | 0.81 | GPR119 (0.50) | TBK1GPR119PIK3CDALOX5APFEN1 | |
| SCHEMBL25211828 | 0.79 | PIK3CD (0.47) | TBK1PIK3CD | |
| SCHEMBL29363431 | 0.79 | PIK3CD (0.47) | TBK1PIK3CD | |
| SCHEMBL21886989 | 0.77 | GPR119 (0.56) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25215026 | 0.76 | PIK3CD (0.43) | TBK1GPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29363625 | 0.76 | PIK3CD (0.43) | TBK1GPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL25029253 | 0.76 | BCL9 (0.46) | TBK1NR3C1 | |
| SCHEMBL30140081 | 0.75 | GPR119 (0.47) | TBK1GPR119PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |