Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.51 |
| ▸ | FABP3 | P05413 | 5/20 | 0.54 |
| ▸ | TERT | O14746 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15365009 | 0.95 | TERT (0.56) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL15365007 | 0.95 | TERT (0.56) | FABP3TERTPTPN1PPARGPPARD | |
| Phosphoric Acid SCHEMBL2926558 | 0.91 | CES2 (0.50) | FAAHKMT2AMEN1LPAR1 | |
| Phosphoric Acid SCHEMBL2935023 | 0.91 | CES2 (0.50) | FAAHKMT2AMEN1LPAR1 | |
| SCHEMBL28770638 | 0.89 | TERT (0.63) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL2139859 | 0.85 | CES2 (0.55) | PPARGPPARDPPARAFAAHKMT2A | |
| SCHEMBL5582211 | 0.85 | CES2 (0.55) | PPARGPPARDPPARAFAAHKMT2A | |
| Phosphoric Acid SCHEMBL28539599 | 0.82 | FABP3 (0.51) | FABP3TERTPTPN1PPARGPPARD | |
| Phosphoric Acid SCHEMBL1690026 | 0.81 | FABP3 (0.50) | FABP3TERTCYP1A2MAPTCYP2C19 | |
| SCHEMBL2936590 | 0.80 | PLA2G4A (0.49) | FABP3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150168419-A1 | PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2015-06-18 | — | — | US | claimed |
| US-20130295679-A1 | PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2013-11-07 | — | — | US | claimed |
| EP-2641092-A1 | PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT | University College Cork - National University of Ireland, Cork (IE) | 2013-09-25 | — | — | EP | claimed |
| WO-2012066057-A1 | PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2012-05-24 | — | — | WO | claimed |
| US-20150168419-A1 | PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2015-06-18 | — | — | US | disclosed |
| US-20130295679-A1 | PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2013-11-07 | — | — | US | disclosed |
| EP-2641092-A1 | PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT | University College Cork - National University of Ireland, Cork (IE) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012066057-A1 | PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2012-05-24 | — | — | WO | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |