Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5461518 | 0.84 | HSP90AA1 (0.53) | CNR2HSP90AA1HSP90AB1NR3C1MET | |
| SCHEMBL3821565 | 0.84 | YTHDC1 (0.57) | HSP90AA1HSP90AB1ADORA2AHDAC4HDAC1 | |
| SCHEMBL5471657 | 0.83 | HSP90AA1 (0.54) | CNR2HSP90AA1HSP90AB1NR3C1MET | |
| SCHEMBL14441142 | 0.83 | HSP90AB1 (0.54) | CNR2HSP90AA1HSP90AB1NR3C1MET | |
| SCHEMBL29366555 | 0.83 | HSP90AA1 (0.54) | CNR2HSP90AA1HSP90AB1NR3C1MET | |
| SCHEMBL29366455 | 0.81 | HSP90AB1 (0.71) | HSP90AA1HSP90AB1ADORA2AHDAC4HDAC1 | |
| SCHEMBL3389606 | 0.81 | HSP90AB1 (0.71) | HSP90AA1HSP90AB1ADORA2AHDAC4HDAC1 | |
| SCHEMBL5460434 | 0.81 | MET (0.48) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL3133524 | 0.81 | CCNE1 (0.53) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL23007800 | 0.80 | CNR2 (0.44) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203159-A1 | Purine compounds | PNP, UMPS, TYMP | PDE4A 414/4885PDE4B 337/4885PDE4C 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.