Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.77 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.77 |
| ▸ | HTT | P42858 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | TP53 | P04637 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 5/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.77 |
| ▸ | USP2 | O75604 | 3/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | EGFR | P00533 | 1/20 | 0.77 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.77 |
| ▸ | LCK | P06239 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodoquinol SCHEMBL29367180 | 0.87 | KDM4E (1.00) | KDM4EHSP90AA1HTTSMN1; SMN2MEN1 | |
| Iodoquinol SCHEMBL3460 | 0.87 | KDM4E (1.00) | KDM4EHSP90AA1HTTSMN1; SMN2MEN1 | |
| Iodoquinol SCHEMBL29606817 | 0.87 | KDM4E (1.00) | KDM4EHSP90AA1HTTSMN1; SMN2MEN1 | |
| Iodoquinol SCHEMBL28519246 | 0.86 | KDM4E (0.96) | KDM4EHSP90AA1HTTSMN1; SMN2MEN1 | |
| Iodoquinol SCHEMBL28518289 | 0.86 | KDM4E (0.96) | KDM4EHSP90AA1HTTSMN1; SMN2MEN1 | |
| Iodoquinol SCHEMBL28536045 | 0.86 | KDM4E (0.96) | KDM4EHSP90AA1HTTSMN1; SMN2MEN1 | |
| Iodoquinol SCHEMBL2532141 | 0.86 | KDM4E (0.96) | KDM4EHSP90AA1HTTSMN1; SMN2MEN1 | |
| Chloroxine SCHEMBL29157288 | 0.77 | KDM4E (0.80) | KDM4EHSP90AA1HTTSMN1; SMN2MEN1 | |
| SCHEMBL29154096 | 0.76 | KDM4E (0.77) | KDM4EHSP90AA1HTTSMN1; SMN2MEN1 | |
| SCHEMBL7772867 | 0.74 | KDM4E (0.68) | KDM4EHSP90AA1HTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001032928-A9 | METHODS OF DETERMINING INDIVIDUAL HYPERSENSITIVITY TO AN AGENT | PHASE 1 MOLECULAR TOXICOLOGY (US) | 2002-05-16 | — | — | WO | disclosed |
| WO-2001032928-A2 | METHODS OF DETERMINING INDIVIDUAL HYPERSENSITIVITY TO AN AGENT | PHASE-1 MOLECULAR TOXICOLOGY (US) | 2001-05-10 | — | — | WO | disclosed |