Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22712485 | 1.00 | MAPT (0.46) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL16635454 | 0.88 | CFTR (0.47) | MAPTRAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL25148607 | 0.83 | LDHA (0.54) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30364708 | 0.83 | LDHA (0.54) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL16635658 | 0.80 | MAPT (0.43) | MAPTGAAPDK2 | |
| SCHEMBL3342506 | 0.77 | KMO (0.48) | MAPTRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL23605339 | 0.76 | SMN1; SMN2 (0.48) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17816222 | 0.76 | MAPT (0.45) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29678882 | 0.76 | RAB9A (0.57) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL22712440 | 0.75 | MAPT (0.40) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215923-B | Macrocyclic broad-spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-115215923-A | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114007605-B | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114007605-A | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-02-01 | — | — | CN | disclosed |