Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 1.00 |
| ▸ | DRD3 | P35462 | 8/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 4/20 | 1.00 |
| ▸ | HTR1A | P08908 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | HTR3A | P46098 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | DRD4 | P21917 | 2/20 | 0.63 |
| ▸ | HTR2A | P28223 | 2/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352699 | 1.00 | DRD2 (1.00) | DRD2DRD3ADRB1HTR1ACYP1A2 | |
| SCHEMBL8511 | 1.00 | DRD2 (1.00) | DRD2DRD3ADRB1HTR1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL2217039 | 0.98 | DRD2 (0.96) | DRD2DRD3ADRB1HTR1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL29470848 | 0.98 | DRD2 (0.96) | DRD2DRD3ADRB1HTR1ACYP1A2 | |
| Bromide SCHEMBL981906 | 0.98 | DRD2 (0.96) | DRD2DRD3ADRB1HTR1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL246338 | 0.98 | DRD2 (0.96) | DRD2DRD3ADRB1HTR1ACYP1A2 | |
| Piperazine SCHEMBL28251276 | 0.98 | DRD2 (0.96) | DRD2DRD3ADRB1HTR1ACYP1A2 | |
| Piperazine SCHEMBL28169968 | 0.96 | DRD2 (0.93) | DRD2DRD3ADRB1HTR1ACYP1A2 | |
| SCHEMBL3609605 | 0.93 | DRD2 (0.87) | DRD2DRD3ADRB1HTR1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL253371 | 0.92 | DRD2 (0.84) | DRD2DRD3ADRB1HTR1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637412-B2 | Preparation of aromatic carboxyamides by a palladium-catalyzed carbonylation reaction | BASF SE (DE) | 2026-05-26 | — | — | US | claimed |
| EP-4143158-B1 | PREPARATION OF AROMATIC CARBOXYAMIDES BY PALLADIUM-CATALYZED CARBONYLATION REACTION | BASF SE (DE) | 2025-10-01 | — | — | EP | claimed |
| CN-120154944-A | Preparation method of capillary electrochromatography monolithic column based on chiral metal organic framework and chiral molecularly imprinted polymer synthesized nano material | 中国药科大学 | 2025-06-17 | — | — | CN | claimed |
| CN-119945759-A | Vulnerability discovery strategy guiding method based on state transition perception | 北京计算机技术及应用研究所 | 2025-05-06 | — | — | CN | claimed |
| CN-118212416-B | Real-time semantic segmentation method for traffic scene image for automatic driving | 天津理工大学 | 2025-02-25 | — | — | CN | claimed |
| CN-114751873-B | Preparation method of 1- (2, 3-dichlorophenyl) piperazine | 扬州市普林斯医药科技有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119219556-A | Method for preparing high-purity aripiprazole | 合肥立方制药股份有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-114539185-B | Preparation method of kalirazine and intermediate thereof | 上海新礼泰药业有限公司 | 2024-12-24 | — | — | CN | claimed |
| CN-114213362-B | Preparation method of calicheazine and intermediate compound | 四川奥邦古得药业有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-115298163-B | Preparation of aromatic carboxamides by palladium catalyzed carbonylation | 巴斯夫欧洲公司 | 2024-11-19 | — | — | CN | claimed |
| CN-114887666-A | Catalyst and application thereof | 山东师范大学 | 2022-08-12 | — | — | CN | claimed |
| CN-114751873-A | Preparation method of 1- (2, 3-dichlorophenyl) piperazine | 扬州市普林斯医药科技有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-114539184-A | Preparation method of cariprazine intermediate | 泰州精英化成医药科技有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-111321092-B | (R, S) -2, 4-dichlorprop degrading strain and dioxygenase gene for specifically degrading (S) -type isomer thereof | 南京农业大学 | 2022-05-24 | — | — | CN | claimed |
| CN-111879767-B | Color development test method of piperazine novel mental active substance | 福建警察学院 | 2022-05-03 | — | — | CN | claimed |
| CN-111795963-B | Method for chromogenic detection of piperazine novel psychotropic active substances | 福建警察学院 | 2022-05-03 | — | — | CN | claimed |
| WO-2022064201-A1 | ANTIMICROBIAL AQUEOUS COATINGS AND SEALANTS | CHEMICAL INTELLIGENCE LIMITED (GB) | 2022-03-31 | — | — | WO | claimed |
| EP-3974480-A1 | ANTIMICROBIAL AQUEOUS COATINGS AND SEALANTS | Chemical Intelligence Limited (GB) | 2022-03-30 | — | — | EP | claimed |
| CN-114213362-A | Preparation method of cariprazine and intermediate compound | 成都栩哲医药科技有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-111378599-B | Degradation strain capable of simultaneously degrading two isomers of chiral herbicide 2, 4-dichlorprop and microbial inoculum produced by same | 南京农业大学 | 2022-02-25 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637412-B2 | Preparation of aromatic carboxyamides by a palladium-catalyzed carbonylation reaction | CBR3, CBR1, AOC1 | DRD2 827/4885DRD3 878/4885ADRB1 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.