Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 15/20 | 0.65 |
| ▸ | CA12 | O43570 | 14/20 | 0.65 |
| ▸ | CA1 | P00915 | 9/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.51 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.51 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.51 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374846 | 0.92 | ALDH1A1 (0.63) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL22516324 | 0.81 | HTT (0.65) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL12585053 | 0.80 | CA9 (0.79) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL22516198 | 0.80 | CA2 (0.68) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL17947763 | 0.78 | CA9 (0.90) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL15838864 | 0.77 | MAPT (0.67) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL16615492 | 0.77 | ALDH1A1 (0.76) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL22516280 | 0.76 | ALDH1A1 (0.60) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL29375406 | 0.76 | ALDH1A1 (0.60) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL6929643 | 0.75 | CA9 (0.74) | CA9CA12CA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946301-A1 | REMODILINS FOR AIRWAY REMODELING AND ORGAN FIBROSIS | The University of Chicago (US) | 2022-02-09 | — | — | EP | disclosed |