Butylscopolamine

Butylscopolamine

SCHEMBL29373202

CCCC[N+]1(C)[C@@H]2CC(OC(=O)[C@H](CO)c3ccccc3)C[C@H]1[C@@H]1O[C@@H]12.[Br-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Butylscopolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 7/20 0.98
CHRM1 known ✓ P11229 5/20 0.98
CHRM5 known ✓ P08912 5/20 0.78
CHRM4 known ✓ P08173 3/20 0.76
CHRM3 known ✓ P20309 3/20 0.76
BLM P54132 5/20 1.00
PMP22 Q01453 2/20 1.00
LMNA P02545 2/20 1.00
TSHR P16473 4/20 0.98
CYP2D6 P10635 1/20 0.98
KCNH2 Q12809 1/20 0.98
HIF1A Q16665 2/20 0.74
CYP3A4 P08684 1/20 0.74
CYP2C9 P11712 1/20 0.74
HSD17B10 Q99714 1/20 0.74
SMN1; SMN2 Q16637 1/20 0.67
CYP1A2 P05177 1/20 0.60
NFKB1 P19838 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylscopolamine SCHEMBL1650352 1.00 BLM (1.00) BLMPMP22LMNACHRM2CHRM1
Butylscopolamine SCHEMBL25292 1.00 BLM (1.00) BLMPMP22LMNACHRM2CHRM1
Butylscopolamine SCHEMBL25291 1.00 BLM (1.00) BLMPMP22LMNACHRM2CHRM1
Butylscopolamine SCHEMBL2441812 1.00 BLM (1.00) BLMPMP22LMNACHRM2CHRM1
Butylscopolamine SCHEMBL5028833 0.99 BLM (0.98) BLMPMP22LMNACHRM2CHRM1
Butylscopolamine SCHEMBL16168163 0.99 CHRM2 (1.00) BLMPMP22LMNACHRM2CHRM1
Butylscopolamine SCHEMBL29643439 0.99 CHRM2 (1.00) BLMPMP22LMNACHRM2CHRM1
Butylscopolamine SCHEMBL2446869 0.99 CHRM2 (1.00) BLMPMP22LMNACHRM2CHRM1
Butylscopolamine SCHEMBL14672547 0.99 CHRM2 (1.00) BLMPMP22LMNACHRM2CHRM1
Butylscopolamine SCHEMBL29473416 0.99 CHRM2 (1.00) BLMPMP22LMNACHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4132565-A1 INDIVIDUALIZED THERAPEUTIC ANTICANCER VACCINE Nykode Therapeutics ASA (NO) 2023-02-15 EP claimed
EP-4303228-B1 LONG-ACTING COAGULATION FACTOR VII AND METHODS OF PRODUCING SAME OPKO BIOLOGICS LTD (IL) 2026-05-27 EP disclosed
WO-2026103808-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF 苏州宜联生物医药有限公司 2026-05-21 WO disclosed
US-12622912-B2 Application of pyrido[1,2-a]pyrimidinone analog Guangzhou Joyo Pharmatech Co., Ltd (CN) 2026-05-12 US disclosed
EP-4729061-A1 USE OF AKT INHIBITOR IN PREPARATION OF DRUG FOR PREVENTING OR TREATING BREAST CANCER Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd. (CN) 2026-04-22 EP disclosed
US-20260097117-A1 CONJUGATES ORUM THERAPEUTICS INC (KR) 2026-04-09 US disclosed
US-20260091033-A1 ANTAGONIST OF THE FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR3) FOR USE IN THE TREATMENT OR THE PREVENTION OF SKELETAL DISORDERS LINKED WITH ABNORMAL ACTIVATION OF FGFR3 INST NAT SANTE RECH MED (FR) 2026-04-02 US disclosed
US-20260070924-A1 INDAZOLE MACROCYCLES AND THEIR USE BLOSSOMHILL THERAPEUTICS INC (US) 2026-03-12 US disclosed
EP-4704915-A1 LINKERS FOR DRUG CONJUGATES AND ANTIBODY DRUG CONJUGATES BioAtla, Inc. (US) 2026-03-11 EP disclosed
CN-121586576-A Application of AKT inhibitor in preparation of medicines for preventing or treating breast cancer 南京正大天晴制药有限公司 2026-02-27 CN disclosed
EP-3979830-A1 PREBIOTIC FORMULATIONS FOR PREVENTION OF SEPSIS AND NECROENTEROCOLITIS INDUCED NEURODEVELOPMENTAL DEFICIENCIES Research Institute at Nationwide Children's Hospital (US) 2022-04-13 EP disclosed
US-20220096645-A1 POLYMER-DRUG CONJUGATES FOR COMBINATION ANTICANCER THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-03-31 US disclosed
EP-3693737-B1 METHOD AND SYSTEM FOR DETERMINING INTEGRATED METABOLIC BASELINE AND POTENTIAL OF LIVING CELLS AGILENT TECHNOLOGIES INC (US) 2022-03-30 EP disclosed
EP-3969116-A1 ACTIVATABLE BISPECIFIC ANTIBODIES COMPRISING A LINKER BETWEEN THE TWO BINDING DOMAINS WHICH IS A HUMAN IMMUNOGLOBULIN HINGE REGION, OR A VARIANT THEREOF, AND USES THEREOF LockBody Therapeutics Ltd (GB) 2022-03-23 EP disclosed
EP-3971175-A1 CRYSTAL FORM OF QUINAZOLINONE COMPOUND AND PREPARATION METHOD THEREFOR Luoxin Healthcare Science and Technology Development (Beijing) Ltd. (CN) 2022-03-23 EP disclosed
US-20220079940-A1 METHODS OF TREATING CANCERS FOGHORN THERAPEUTICS INC. 2022-03-17 US disclosed
EP-3961742-A1 ORGANIC SEMICONDUCTIVE LAYER COMPRISING PHOSPHINE OXIDE COMPOUNDS Novaled GmbH (DE) 2022-03-02 EP disclosed
CN-109908334-B Tumor vaccine and preparation method and application thereof 四川大学 2022-02-15 CN disclosed
US-11246873-B2 Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate THE SCRIPPS RESEARCH INSTITUTE (US) 2022-02-15 US disclosed
US-20220031696-A9 ANTAGONIST OF THE FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR3) FOR USE IN THE TREATMENT OR THE PREVENTION OF SKELETAL DISORDERS LINKED WITH ABNORMAL ACTIVATION OF FGFR3 UNIVERSITÉ PARIS CITÉ (FR) 2022-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097117-A1 CONJUGATES CRBN, CUL4B, CUL4A CHRM2 1176/4885CHRM1 1268/4885CHRM5 1059/4885
US-20260091033-A1 ANTAGONIST OF THE FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR3) FOR USE IN THE TREATMENT OR THE PREVENTION OF SKELETAL DISORDERS LINKED WITH ABNORMAL ACTIVATION OF FGFR3 FGFR3, FGF23, FGFR2 CHRM2 3054/4885CHRM1 3607/4885CHRM5 3329/4885
US-20260070924-A1 INDAZOLE MACROCYCLES AND THEIR USE NR0B2, NR0B1, ESRRA CHRM2 1856/4885CHRM1 2131/4885CHRM5 1342/4885
US-20220096645-A1 POLYMER-DRUG CONJUGATES FOR COMBINATION ANTICANCER THERAPY TOP2A, TOP1, TOP2B CHRM2 4585/4885CHRM1 4525/4885CHRM5 4699/4885
US-12622912-B2 Application of pyrido[1,2-a]pyrimidinone analog PIK3CA, BRCA1, PIK3CD CHRM2 4530/4885CHRM1 4092/4885CHRM5 4718/4885
US-20220031696-A9 ANTAGONIST OF THE FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR3) FOR USE IN THE TREATMENT OR THE PREVENTION OF SKELETAL DISORDERS LINKED WITH ABNORMAL ACTIVATION OF FGFR3 FGFR3, FGFR1, FGFR2 CHRM2 4400/4885CHRM1 4626/4885CHRM5 4655/4885
US-20220079940-A1 METHODS OF TREATING CANCERS MCL1, BRPF3, VHL CHRM2 4866/4885CHRM1 4875/4885CHRM5 4837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.