SCHEMBL29374017

SCHEMBL29374017

O=CC(O)c1ccc(O)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 9/20 0.48
▸ RECQL P46063 8/20 0.48
▸ KDM4E B2RXH2 8/20 0.48
▸ MAPT P10636 7/20 0.48
▸ BLM P54132 5/20 0.48
▸ LMNA P02545 5/20 0.48
▸ APEX1 P27695 4/20 0.48
▸ KMT2A Q03164 4/20 0.48
▸ ADRA1A P35348 3/20 0.48
▸ PTGS2 P35354 3/20 0.48
▸ MEN1 O00255 3/20 0.48
▸ MAPK1 P28482 3/20 0.48
▸ HPGD P15428 2/20 0.48
▸ ADRB2 P07550 2/20 0.48
▸ ADRB1 P08588 2/20 0.48
▸ ADRA2A P08913 2/20 0.48
▸ ADORA3 P0DMS8 2/20 0.48
▸ ADRB3 P13945 2/20 0.48
▸ DRD2 P14416 2/20 0.48
▸ ADRA2B P18089 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1332823 1.00 TDP1 (0.48) TDP1RECQLKDM4EMAPTBLM
SCHEMBL13176447 0.78 TDP1 (0.48) TDP1RECQLKDM4EMAPTBLM
SCHEMBL2506281 0.77 TSHR (0.61) TDP1BLMKMT2AMEN1HPGD
SCHEMBL30924863 0.77 TSHR (0.61) TDP1BLMKMT2AMEN1HPGD
Formic Acid SCHEMBL29183960 0.77 TDP1 (0.55) TDP1RECQLKDM4EMAPTBLM
SCHEMBL15973924 0.77 KDM4E (0.43) TDP1RECQLKDM4EMAPTBLM
SCHEMBL15688141 0.77 SHBG (0.44) TDP1RECQLKDM4EMAPTBLM
SCHEMBL20361608 0.77 TDP1 (0.50) TDP1RECQLKDM4EMAPTBLM
SCHEMBL28165577 0.77 TDP1 (0.50) TDP1RECQLKDM4EMAPTBLM
SCHEMBL7192542 0.77 TDP1 (0.50) TDP1RECQLKDM4EMAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116990405-A Marker for predicting curative effect of ketamine on treating depression, screening method and application thereof 广州医科大学附属脑科医院 2023-11-03 — — CN claimed
US-12582704-B2 Food composition for improving behavioral and motor function containing aldehyde dehydrogenase for reducing aldehydes produced by oxidation of alcohol PICOENTECH Co., LTD. (KR) 2026-03-24 — — US disclosed
EP-4704971-A1 GAMMA STIMULATION AND NEUROMODULATOR COMBINATION THERAPY Cognito Therapeutics, Inc. (US) 2026-03-11 — — EP disclosed
US-20250360285-A1 SENSORY GAMMA STIMULATION THERAPY IMPROVES SLEEP QUALITY AND MAINTAINS FUNCTIONAL ABILITY IN ALZHEIMERS DISEASE PATIENTS COGNITO THERAPEUTICS INC (US) 2025-11-27 — — US disclosed
EP-4627069-A1 FOOD AND PHARMACEUTICAL COMPOSITION FOR DETOXIFYING ENDOGENOUS ALDEHYDES Picoentech Co., Ltd. (KR) 2025-10-08 — — EP disclosed
EP-4626259-A1 NOVEL ALDEHYDE DEHYDROGENASE FOOD AND DRUG COMPOSITION FOR IMPROVING BEHAVIOR AND MOTOR FUNCTION Picoentech Co., Ltd. (KR) 2025-10-08 — — EP disclosed
US-20250152601-A1 Compositions and Methods for the Treatment of Sexual Dysfunctions THE JONATHAN HURT LIVING TRUST (US) 2025-05-15 — — US disclosed
US-20250154550-A1 HANGOVER RELIEVER CONTAINING GLUTATHIONE AND ALDEHYDE DEHYDROGENASE PICO ENTECH CO., LTD. (KR) 2025-05-15 — — US disclosed
CN-118325814-B Sophora japonica exosomes and application thereof in preparation of drugs for treating damage to digestive tract mucous membrane barrier 中国人民解放军总医院第一医学中心 2025-04-22 — — CN disclosed
US-20250090642-A1 FOOD COMPOSITION FOR IMPROVING BEHAVIORAL AND MOTOR FUNCTION CONTAINING ALDEHYDE DEHYDROGENASE FOR REDUCING ALDEHYDES PRODUCED BY OXIDATION OF AMINE PICOENTECH Co., LTD. (KR) 2025-03-20 — — US disclosed
US-20230111776-A1 METHODS OF ENHANCING NEUROSTIMULATION DURING ACTIVITIES HERCULES CAPITAL, INC. 2023-04-13 — — US disclosed
US-20230104621-A1 ENTERTAINMENT DEVICE FOR PROMOTING GAMMA OSCILATIONS HERCULES CAPITAL, INC. 2023-04-06 — — US disclosed
WO-2023049470-A1 METHODS OF ENHANCING NEUROSTIMULATION DURING ACTIVITIES Cognito Therapeutics, Inc. (US) 2023-03-30 — — WO disclosed
WO-2023049467-A1 ENTERTAINMENT DEVICE FOR PROMOTING GAMMA OSCILLATIONS Cognito Therapeutics, Inc. (US) 2023-03-30 — — WO disclosed
US-20230051207-A1 HANGOVER RELIEVER CONTAINING GLUTATHIONE AND ALDEHYDE DEHYDROGENASE PICO ENTECH CO., LTD. (KR) 2023-02-16 — — US disclosed
EP-3611159-B1 DIHYDROXYPHENYL NEUROTRANSMITTER COMPOUNDS, COMPOSITIONS AND METHODS AUSPEX PHARMACEUTICALS INC (US) 2023-01-25 — — EP disclosed
CN-115087726-A Hangover relief agent containing glutathione and aldehyde dehydrogenase 匹克生物酶高科技有限公司 2022-09-20 — — CN disclosed
US-20220229077-A1 DIAGNOSIS, PROGNOSIS AND TREATMENT FOR SCHIZOPHRENIA AND SCHIZOAFFECTIVE PSYCHOSIS PRECISION MEDICINE HOLDINGS PTY LTD (AU) 2022-07-21 — — US disclosed
US-20220072131-A1 Dihydroxyphenyl Neurotransmitter Compounds, Compositions And Methods AUSPEX PHARMACEUTICALS INC (US) 2022-03-10 — — US disclosed
WO-2022027030-A1 SENSORY GAMMA STIMULATION THERAPY IMPROVES SLEEP QUALITY AND MAINTAINS FUNCTIONAL ABILITY IN ALZHEIMERS DISEASE PATIENTS Cognito Therapeutics, Inc. (US) 2022-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220072131-A1 Dihydroxyphenyl Neurotransmitter Compounds, Compositions And Methods SLC18A2, COMT, SLC6A2 TDP1 1161/4885RECQL 1726/4885KDM4E 1137/4885
US-12582704-B2 Food composition for improving behavioral and motor function containing aldehyde dehydrogenase for reducing aldehydes produced by oxidation of alcohol ADH1C, ADH1A, ALDH2 TDP1 315/4885RECQL 1194/4885KDM4E 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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