SCHEMBL29374041

SCHEMBL29374041

COC(=O)CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(=O)OC)C(=O)CF

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 11/20 0.54
▸ MMP3 P08254 1/20 0.54
▸ CTSB P07858 1/20 0.54
▸ CTSK P43235 1/20 0.54
▸ MME P08473 1/20 0.48
▸ ECE1 P42892 1/20 0.48
▸ CAPN1 P07384 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29432617 0.93 REN (0.53) RENMMP3CTSBCTSKMME
SCHEMBL20257141 0.89 CTSK (0.56) RENCTSBCTSKCAPN1
SCHEMBL23133192 0.89 CTSK (0.56) RENCTSBCTSKCAPN1
SCHEMBL29392130 0.88 NMBR (0.58) REN
SCHEMBL23133281 0.86 REN (0.48) RENCTSBCTSKCAPN1
SCHEMBL20257155 0.86 REN (0.48) RENCTSBCTSKCAPN1
SCHEMBL20257150 0.84 CTSK (0.51) RENCTSBCTSKCAPN1
SCHEMBL21481101 0.84 CTSK (0.56) RENCTSBCTSKCAPN1
SCHEMBL21481102 0.84 CTSK (0.56) RENCTSBCTSKCAPN1
SCHEMBL23613619 0.84 CTSL (0.48) RENCTSBCTSKCAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240365773-A1 USE OF APOPTOSIS INHIBITORS FOR COLD STORAGE OF BLOOD PLATELETS ZENTRUM FÜR KLINISCHE TRANSFUSIONSMEDIZIN TÜBINGEN GGMBH (ZKT) (DE) 2024-11-07 — — US claimed
CN-118120736-A Intestinal tissue preservation solution and preservation method and application thereof 江苏齐氏生物科技有限公司 2024-06-04 — — CN claimed
CN-118044505-A Fresh tissue preservation solution and preparation method and application thereof 北京百奥智汇科技有限公司 2024-05-17 — — CN claimed
US-20240115649-A1 CASPASE INHIBITION TO ENHANCE REGENERATION AND REPAIR AFTER SKIN OR GUT INJURY AND TO TREAT BACTERIAL OR VIRAL INFECTIONS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-04-11 — — US claimed
EP-4326060-A1 USE OF APOPTOSIS INHIBITORS FOR COLD STORAGE OF BLOOD PLATELETS DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH (DE) 2024-02-28 — — EP claimed
US-11618883-B2 Method for producing retinal pigment epithelial cells Sumitomo Pharma Co., Ltd. (JP) 2023-04-04 — — US claimed
WO-2022223815-A1 USE OF APOPTOSIS INHIBITORS FOR COLD STORAGE OF BLOOD PLATELETS DRK BLUTSPENDEDIENST BADEN-WÜRTTEMBERG-HESSEN GGMBH (DE) 2022-10-27 — — WO claimed
EP-4079154-A1 USE OF APOPTOSIS INHIBITORS FOR COLD STORAGE OF BLOOD PLATELETS DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH (DE) 2022-10-26 — — EP claimed
CN-115197913-A Primary corneal endothelial cell culture solution and application thereof 江苏齐氏生物科技有限公司 2022-10-18 — — CN claimed
CN-114586768-A Liver tissue preservation solution and preservation method and application thereof 江苏齐氏生物科技有限公司 2022-06-07 — — CN claimed
EP-4709405-A2 FLUORESCEIN-LABELED NERVE TARGETING PEPTIDE FORMULATIONS AND RELATED METHODS Alume Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
US-12533425-B2 Methods and systems using peptides for targeting and mapping human nerves in image guided surgery, diagnostics and therapeutic delivery ALUME BIOSCIENCES, INC. (US) 2026-01-27 — — US disclosed
US-20250216377-A1 COMPOSITIONS AND METHODS FOR DETECTING CARDIOTOXICITY AGEX THERAPEUTICS, INC. (US) 2025-07-03 — — US disclosed
US-12344599-B2 Prodigiosin analogs and methods of use INSTITUTE FOR CANCER RESEARCH (US) 2025-07-01 — — US disclosed
WO-2025128913-A1 INHIBITION OF ENDOSOMAL ESCAPE DETECTION TO AMELIORATE THE INFLAMMATORY SIDE-EFFECTS OF LIPID NANOPARTICLES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-06-19 — — WO disclosed
US-20220118101-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING INFLAMMATION BY INHIBITING CASPASE-9 UNIV COLUMBIA (US) 2022-04-21 — — US disclosed
US-11299515-B2 Optimized peptides for targeting human nerves and their use in image guided surgery, diagnostics and therapeutic THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-12 — — US disclosed
CN-107921094-B IGFBP3 and uses thereof 圣拉斐尔医院有限公司 2022-03-01 — — CN disclosed
US-11246940-B2 Peptides whose uptake in cells is controllable THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-02-15 — — US disclosed
US-20220033382-A9 Prodigiosin Analogs And Methods Of Use INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER 2022-02-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344599-B2 Prodigiosin analogs and methods of use TP53, MCL1, TP53BP1 REN 4017/4885MMP3 1564/4885CTSB 297/4885
US-12533425-B2 Methods and systems using peptides for targeting and mapping human nerves in image guided surgery, diagnostics and therapeutic delivery NGLY1, VGF, GAP43 REN 3526/4885MMP3 2597/4885CTSB 4255/4885
US-20220033382-A9 Prodigiosin Analogs And Methods Of Use TP53, MCL1, TP53BP1 REN 4017/4885MMP3 1564/4885CTSB 297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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