Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 5/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20257141 | 1.00 | CTSK (0.56) | CTSKCAPN1CTSLCTSSCTSB | |
| SCHEMBL20257150 | 0.95 | CTSK (0.51) | CTSKCAPN1CTSLCTSSCTSB | |
| SCHEMBL21481101 | 0.95 | CTSK (0.56) | CTSKCAPN1CTSBREN | |
| SCHEMBL21481102 | 0.95 | CTSK (0.56) | CTSKCAPN1CTSBREN | |
| SCHEMBL23133259 | 0.94 | REN (0.51) | CTSKCAPN1CTSLCTSSCTSB | |
| SCHEMBL23133260 | 0.94 | REN (0.51) | CTSKCAPN1CTSLCTSSCTSB | |
| SCHEMBL29946166 | 0.94 | REN (0.51) | CTSKCAPN1CTSLCTSSCTSB | |
| SCHEMBL20257224 | 0.94 | REN (0.51) | CTSKCAPN1CTSLCTSSCTSB | |
| SCHEMBL23613597 | 0.91 | REN (0.49) | CTSKCAPN1CTSLCTSSCTSB | |
| SCHEMBL23613619 | 0.90 | CTSL (0.48) | CTSKCAPN1CTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210088504-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210088504-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | SENP8, SENP6, SENP7 | CTSK 914/4885CAPN1 798/4885CTSL 1364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.