Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 7/20 | 1.00 |
| ▸ | MAP3K9 | P80192 | 6/20 | 1.00 |
| ▸ | PRKCA | P17252 | 4/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 3/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 3/20 | 1.00 |
| ▸ | GLI1 | P08151 | 2/20 | 1.00 |
| ▸ | GLI2 | P10070 | 2/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 2/20 | 1.00 |
| ▸ | PRKCG | P05129 | 2/20 | 1.00 |
| ▸ | PRKCB | P05771 | 2/20 | 1.00 |
| ▸ | PRKCH | P24723 | 2/20 | 1.00 |
| ▸ | PRKCI | P41743 | 2/20 | 1.00 |
| ▸ | PRKCE | Q02156 | 2/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 2/20 | 1.00 |
| ▸ | PRKD1 | Q15139 | 2/20 | 1.00 |
| ▸ | CDK4 | P11802 | 1/20 | 1.00 |
| ▸ | CTRB1 | P17538 | 1/20 | 1.00 |
| ▸ | PRKACA | P17612 | 1/20 | 1.00 |
| ▸ | PRKACG | P22612 | 1/20 | 1.00 |
| ▸ | PRKACB | P22694 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Staurosporinone SCHEMBL5440281 | 1.00 | MAP3K11 (1.00) | MAP3K11MAP3K9PRKCAPRKCQPRKCD | |
| Staurosporinone SCHEMBL29389399 | 1.00 | MAP3K11 (1.00) | MAP3K11MAP3K9PRKCAPRKCQPRKCD | |
| SCHEMBL9263371 | 0.88 | MAP3K11 (0.78) | MAP3K11MAP3K9PRKCAPRKCQPRKCD | |
| SCHEMBL9270827 | 0.88 | MAP3K11 (0.78) | MAP3K11MAP3K9PRKCAPRKCQPRKCD | |
| SCHEMBL9260091 | 0.85 | ROCK2 (0.78) | MAP3K11MAP3K9PRKCAPRKCQPRKCD | |
| SCHEMBL9263506 | 0.85 | ROCK2 (0.78) | MAP3K11MAP3K9PRKCAPRKCQPRKCD | |
| SCHEMBL13639843 | 0.83 | MAP3K11 (1.00) | MAP3K11MAP3K9PRKCAPRKCQPRKCD | |
| SCHEMBL13639845 | 0.83 | MAP3K11 (1.00) | MAP3K11MAP3K9PRKCAPRKCQPRKCD | |
| SCHEMBL13140090 | 0.83 | MAP3K11 (1.00) | MAP3K11MAP3K9PRKCAPRKCQPRKCD | |
| SCHEMBL13431719 | 0.82 | MAP3K11 (0.69) | MAP3K11MAP3K9PRKCAPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169609-A1 | INDOLE-YNONE MEDIATED BENZOANNULATION PROCESS FOR THE PREPARATION OF CARBAZOLES, CARBAZOMYCIN A, CALOTHRIXIN B AND STAUROSPORINONE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-06-02 | — | — | US | claimed |
| US-20220125834-A1 | LOCALIZED DELIVERY OF THERAPEUTIC AGENTS | Nostopharma, LLC | 2022-04-28 | — | — | US | claimed |
| EP-3947333-A1 | INDOLE-YNONE MEDIATED BENZOANNULATION PROCESS FOR THE PREPARATION OF CARBAZOLES- CARBAZOMYCIN A, CALOTHRIXIN B AND STAUROSPORINONE | Council of Scientific & Industrial Research (IN) | 2022-02-09 | — | — | EP | claimed |
| EP-4713340-A2 | COMPOSITIONS AND METHODS FOR PEPTIDE-BASED MODULATORS OF HUMAN PAPILLOMAVIRUS ONCOPROTEIN E6 | Calico Life Sciences LLC (US) | 2026-03-25 | — | — | EP | disclosed |
| US-12459893-B2 | Indole-ynone mediated benzoannulation process for the preparation of carbazoles, carbazomycin A, calothrixin B and staurosporinone | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2025-11-04 | — | — | US | disclosed |
| US-12459893-B2 | Indole-ynone mediated benzoannulation process for the preparation of carbazoles, carbazomycin A, calothrixin B and staurosporinone | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2025-11-04 | — | — | US | disclosed |
| US-12459893-B2 | Indole-ynone mediated benzoannulation process for the preparation of carbazoles, carbazomycin A, calothrixin B and staurosporinone | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2025-11-04 | — | — | US | disclosed |
| US-20250304916-A1 | METHODS AND COMPOSITIONS FOR GENERATING VASCULAR LEPTOMENINGEAL CELLS | TRAILHEAD BIOSYSTEMS INC (US) | 2025-10-02 | — | — | US | disclosed |
| WO-2025111511-A2 | REVERSIBLY REACTIVE AFFINITY SELECTION MASS SPECTROMETRY AND USES THEREOF | CALICO LIFE SCIENCES LLC (US) | 2025-05-30 | — | — | WO | disclosed |
| US-12209092-B2 | Inhibitors of GLI1 as therapeutic agents | NEW YORK UNIVERSITY (US) | 2025-01-28 | — | — | US | disclosed |
| EP-3609500-B1 | TREATMENT OF ADIPOCYTES | MELIOR PHARMACEUTICALS I INC (US) | 2024-11-13 | — | — | EP | disclosed |
| US-11377636-B2 | Endogenous retrovirus transcription as a marker for primate naive pluripotent stem cells | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (DE) | 2022-07-05 | — | — | US | disclosed |
| US-20220186227-A1 | Therapeutic Targets for Oncogenic KRAS-Dependent Cancers | UNIVERSITY OF MASSACHUSETTS | 2022-06-16 | — | — | US | disclosed |
| US-20220169609-A1 | INDOLE-YNONE MEDIATED BENZOANNULATION PROCESS FOR THE PREPARATION OF CARBAZOLES, CARBAZOMYCIN A, CALOTHRIXIN B AND STAUROSPORINONE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-06-02 | — | — | US | disclosed |
| US-20220169609-A1 | INDOLE-YNONE MEDIATED BENZOANNULATION PROCESS FOR THE PREPARATION OF CARBAZOLES, CARBAZOMYCIN A, CALOTHRIXIN B AND STAUROSPORINONE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-06-02 | — | — | US | disclosed |
| US-20220169609-A1 | INDOLE-YNONE MEDIATED BENZOANNULATION PROCESS FOR THE PREPARATION OF CARBAZOLES, CARBAZOMYCIN A, CALOTHRIXIN B AND STAUROSPORINONE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-06-02 | — | — | US | disclosed |
| US-20220125834-A1 | LOCALIZED DELIVERY OF THERAPEUTIC AGENTS | Nostopharma, LLC | 2022-04-28 | — | — | US | disclosed |
| EP-3947333-A1 | INDOLE-YNONE MEDIATED BENZOANNULATION PROCESS FOR THE PREPARATION OF CARBAZOLES- CARBAZOMYCIN A, CALOTHRIXIN B AND STAUROSPORINONE | Council of Scientific & Industrial Research (IN) | 2022-02-09 | — | — | EP | disclosed |
| EP-3947333-A1 | INDOLE-YNONE MEDIATED BENZOANNULATION PROCESS FOR THE PREPARATION OF CARBAZOLES- CARBAZOMYCIN A, CALOTHRIXIN B AND STAUROSPORINONE | Council of Scientific & Industrial Research (IN) | 2022-02-09 | — | — | EP | disclosed |
| EP-3947333-A1 | INDOLE-YNONE MEDIATED BENZOANNULATION PROCESS FOR THE PREPARATION OF CARBAZOLES- CARBAZOMYCIN A, CALOTHRIXIN B AND STAUROSPORINONE | Council of Scientific & Industrial Research (IN) | 2022-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12209092-B2 | Inhibitors of GLI1 as therapeutic agents | GLI1, GLI2, SHH | MAP3K11 2207/4885MAP3K9 2437/4885PRKCA 448/4885 |
| US-12459893-B2 | Indole-ynone mediated benzoannulation process for the preparation of carbazoles, carbazomycin A, calothrixin B and staurosporinone | CYC1, CYCS, CANX | MAP3K11 2101/4885MAP3K9 2007/4885PRKCA 1509/4885 |
| US-20220169609-A1 | INDOLE-YNONE MEDIATED BENZOANNULATION PROCESS FOR THE PREPARATION OF CARBAZOLES, CARBAZOMYCIN A, CALOTHRIXIN B AND STAUROSPORINONE | CYC1, CYCS, CANX | MAP3K11 2101/4885MAP3K9 2007/4885PRKCA 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.