Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 9/20 | 0.47 |
| ▸ | CA2 | P00918 | 9/20 | 0.47 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL816807 | 1.00 | RECQL (0.71) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL819036 | 1.00 | RECQL (0.71) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL5513988 | 1.00 | RECQL (0.71) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL1352916 | 1.00 | RECQL (0.71) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL29371821 | 1.00 | RECQL (0.71) | RECQLTSHRGLAHPGDMAPK1 | |
| Lithium Ion SCHEMBL17456371 | 0.96 | RECQL (0.71) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL2730477 | 0.96 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL15206914 | 0.96 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL818230 | 0.96 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL818842 | 0.96 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242462-B2 | Method for producing polymer emulsion for water-resistant coating film | KAO CORPORATION (JP) | 2022-02-08 | — | — | US | disclosed |