SCHEMBL29375129

SCHEMBL29375129

O=C(Nc1ccc(Cl)cc1)c1cc(Cl)cc(Cl)c1O

nearest known ligand 0.77

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.77
TBXAS1 P24557 1/20 0.77
MAPK1 P28482 1/20 0.77
PTGS2 P35354 1/20 0.77
MAPK14 Q16539 1/20 0.77
STK39 Q9UEW8 11/20 0.70
PNLIP P16233 1/20 0.69
P2RX1 P51575 1/20 0.66
PARG Q86W56 3/20 0.64
BCL2L1 Q07817 1/20 0.60
CTSD P07339 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL649911 1.00 PTGS1 (0.77) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL21570088 0.91 STK39 (0.85) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL11692717 0.89 PTGS1 (0.71) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL10457403 0.89 PARG (0.71) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL25413048 0.89 PTGS1 (0.71) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL9868077 0.89 STK39 (0.77) PTGS1TBXAS1MAPK1PTGS2MAPK14
3,3',4',5-Tetrachlorosalicylanilide SCHEMBL29367227 0.87 PTGS1 (1.00) PTGS1TBXAS1MAPK1PTGS2MAPK14
3,3',4',5-Tetrachlorosalicylanilide SCHEMBL168748 0.87 PTGS1 (1.00) PTGS1TBXAS1MAPK1PTGS2MAPK14
Hydrochloric Acid SCHEMBL11777767 0.87 STK39 (0.75) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL29211122 0.85 P2RX1 (0.64) PTGS1TBXAS1MAPK1PTGS2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250376550-A1 PARTICLES USED FOR FORMATION OF PICKERING EMULSION OR LIKE KIRIN HOLDINGS KABUSHIKI KAISHA (JP) 2025-12-11 US disclosed
EP-4538328-A1 PARTICLES USED FOR FORMATION OF PICKERING EMULSION OR LIKE KIRIN HOLDINGS KABUSHIKI KAISHA (JP) 2025-04-16 EP disclosed
WO-2023243633-A1 PARTICLES USED FOR FORMATION OF PICKERING EMULSION OR LIKE キリンホールディングス株式会社 2023-12-21 WO disclosed
US-11844813-B2 Ligand regulated protein-protein interaction system ST. ANNA KINDERKREBSFORSCHUNG (AT) 2023-12-19 US disclosed
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) ST. ANNA KINDERKREBSFORSCHUNG (AT) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) CARS1, CD74, HAVCR2 PTGS1 3901/4885TBXAS1 4256/4885MAPK1 4128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.