Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK39 | Q9UEW8 | 12/20 | 0.77 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.70 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.70 |
| ▸ | PARG | Q86W56 | 3/20 | 0.66 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.65 |
| ▸ | ACLY | P53396 | 1/20 | 0.61 |
| ▸ | CTSD | P07339 | 1/20 | 0.58 |
| ▸ | PNLIP | P16233 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11777767 | 0.98 | STK39 (0.75) | STK39PTGS1TBXAS1MAPK1PTGS2 | |
| SCHEMBL29375129 | 0.89 | PTGS1 (0.77) | STK39PTGS1TBXAS1MAPK1PTGS2 | |
| SCHEMBL649911 | 0.89 | PTGS1 (0.77) | STK39PTGS1TBXAS1MAPK1PTGS2 | |
| SCHEMBL8672680 | 0.88 | PTGS1 (0.71) | STK39PTGS1TBXAS1MAPK1PTGS2 | |
| SCHEMBL25413048 | 0.84 | PTGS1 (0.71) | STK39PTGS1TBXAS1MAPK1PTGS2 | |
| SCHEMBL10457403 | 0.84 | PARG (0.71) | STK39PTGS1TBXAS1MAPK1PTGS2 | |
| SCHEMBL11692717 | 0.84 | PTGS1 (0.71) | STK39PTGS1TBXAS1MAPK1PTGS2 | |
| SCHEMBL5658052 | 0.83 | PTGS1 (0.64) | STK39PTGS1TBXAS1MAPK1PTGS2 | |
| 3,3',4',5-Tetrachlorosalicylanilide SCHEMBL29367227 | 0.83 | PTGS1 (1.00) | STK39PTGS1TBXAS1MAPK1PTGS2 | |
| 3,3',4',5-Tetrachlorosalicylanilide SCHEMBL168748 | 0.83 | PTGS1 (1.00) | STK39PTGS1TBXAS1MAPK1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412211-A1 | Cancer therapy system | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1991-02-13 | — | — | EP | disclosed |
| US-4935450-A | Cancer therapy system for effecting oncolysis of malignant neoplasms | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4724234-A | ADMINISTERING NUTRITIONAL REGIMEN AND AGENTS WHICH UNCOUPLE OXIDATIVE PHOSPHORYLATION | THERAPEUTICAL SYSTEMS CORP. (US) | 1988-02-09 | — | — | US | disclosed |