SCHEMBL29375169

SCHEMBL29375169

COc1ccc(C2(c3ccc(OC)cc3)C=Cc3c(cc(N4CCOCC4)c4ccccc34)O2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 7/20 0.41
MAPT P10636 5/20 0.40
NPSR1 Q6W5P4 3/20 0.40
KDM4E B2RXH2 3/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.40
BLM P54132 1/20 0.40
POLB P06746 2/20 0.39
MERTK Q12866 1/20 0.37
NCF1 P14598 1/20 0.37
ALDH1A1 P00352 3/20 0.37
TSHR P16473 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2456236 1.00 PRKDC (0.41) PRKDCMAPTNPSR1KDM4ECYP3A4
SCHEMBL2417015 0.98 PRKDC (0.40) PRKDCMAPTNPSR1KDM4ECYP3A4
SCHEMBL12205748 0.96 PRKDC (0.39) PRKDCMAPTNPSR1KDM4ECYP3A4
SCHEMBL14607589 0.95 POLB (0.40) PRKDCMAPTNPSR1KDM4ECYP3A4
SCHEMBL12259684 0.94 PRKDC (0.39) PRKDCMAPTNPSR1KDM4ECYP3A4
SCHEMBL7471010 0.93 NPSR1 (0.37) PRKDCMAPTNPSR1KDM4ECYP3A4
SCHEMBL5707975 0.93 MAPT (0.38) PRKDCMAPTNPSR1KDM4ECYP3A4
SCHEMBL8845387 0.93 LMNA (0.38) PRKDCMAPTNPSR1KDM4ECYP3A4
SCHEMBL12377275 0.91 MAPT (0.39) PRKDCMAPTNPSR1KDM4ECYP3A4
SCHEMBL8845473 0.91 MAPT (0.40) PRKDCMAPTNPSR1KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12232593-B2 Method for shaping an applicator for applying a cosmetic composition L'OREAL (FR) 2025-02-25 US disclosed
CN-114025640-B Device for picking up and applying a cosmetic product 欧莱雅 2024-11-12 CN disclosed
EP-3086853-B1 MAKEUP DEVICE COMPRISING A PLURALITY OF COSMETIC DYES OREAL (FR) 2023-08-09 EP disclosed
EP-4051053-A1 SYSTEM FOR TAKING UP AND APPLYING A COSMETIC COMPOSITION L'OREAL (FR) 2022-09-07 EP disclosed
US-20220256996-A1 METHOD FOR SHAPING AN APPLICATOR FOR APPLYING A COSMETIC COMPOSITION L'OREAL (FR) 2022-08-18 US disclosed
CN-114615912-A System for picking up and applying a cosmetic composition 欧莱雅 2022-06-10 CN disclosed
EP-3989769-A1 DEVICE FOR PICKING UP AND APPLYING A COSMETIC PRODUCT L'OREAL (FR) 2022-05-04 EP disclosed
EP-3989772-A1 METHOD FOR SHAPING AN APPLICATOR FOR APPLYING A COSMETIC COMPOSITION L'OREAL (FR) 2022-05-04 EP disclosed
CN-114080171-A Method for forming an applicator for applying a cosmetic composition 欧莱雅 2022-02-22 CN disclosed
CN-114025640-A Device for picking up and applying a cosmetic product 欧莱雅 2022-02-08 CN disclosed