Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 3/20 | 0.37 |
| ▸ | PRKDC | P78527 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456236 | 0.93 | PRKDC (0.41) | NPSR1KDM4ESMN1; SMN2L3MBTL1POLB | |
| SCHEMBL29375169 | 0.93 | PRKDC (0.41) | NPSR1KDM4ESMN1; SMN2L3MBTL1POLB | |
| SCHEMBL5615614 | 0.92 | KMT2A (0.41) | NPSR1KDM4ESMN1; SMN2POLBALDH1A1 | |
| SCHEMBL2417015 | 0.92 | PRKDC (0.40) | NPSR1KDM4ESMN1; SMN2L3MBTL1POLB | |
| SCHEMBL8506443 | 0.92 | NPSR1 (0.40) | NPSR1KDM4ESMN1; SMN2L3MBTL1POLB | |
| SCHEMBL29501170 | 0.91 | ALDH1A1 (0.41) | NPSR1KDM4ESMN1; SMN2L3MBTL1POLB | |
| SCHEMBL2412684 | 0.91 | ALDH1A1 (0.41) | NPSR1KDM4ESMN1; SMN2L3MBTL1POLB | |
| SCHEMBL12205748 | 0.90 | PRKDC (0.39) | NPSR1KDM4ESMN1; SMN2L3MBTL1POLB | |
| SCHEMBL2599669 | 0.90 | KDM4E (0.39) | NPSR1KDM4ESMN1; SMN2L3MBTL1POLB | |
| SCHEMBL14607589 | 0.89 | POLB (0.40) | NPSR1KDM4ESMN1; SMN2L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973761-B1 | RED COLOURING HYPERCHROMIC 3H-NAPHTHO 2,1-b ]PYRANS | JAMES ROBINSON LTD (GB) | 2002-07-03 | — | — | EP | claimed |
| US-6294112-B1 | Red coloring hyperchromic 3H-naphtho[2,1-B]pyrans | JAMES ROBINSON LIMITED (GB) | 2001-09-25 | — | — | US | claimed |
| EP-0973761-B1 | RED COLOURING HYPERCHROMIC 3H-NAPHTHO 2,1-b ]PYRANS | JAMES ROBINSON LTD (GB) | 2002-07-03 | — | — | EP | disclosed |
| US-6294112-B1 | Red coloring hyperchromic 3H-naphtho[2,1-B]pyrans | JAMES ROBINSON LIMITED (GB) | 2001-09-25 | — | — | US | disclosed |