Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375169 | 1.00 | PRKDC (0.41) | PRKDCMAPTNPSR1KDM4ECYP3A4 | |
| SCHEMBL2417015 | 0.98 | PRKDC (0.40) | PRKDCMAPTNPSR1KDM4ECYP3A4 | |
| SCHEMBL12205748 | 0.96 | PRKDC (0.39) | PRKDCMAPTNPSR1KDM4ECYP3A4 | |
| SCHEMBL14607589 | 0.95 | POLB (0.40) | PRKDCMAPTNPSR1KDM4ECYP3A4 | |
| SCHEMBL12259684 | 0.94 | PRKDC (0.39) | PRKDCMAPTNPSR1KDM4ECYP3A4 | |
| SCHEMBL7471010 | 0.93 | NPSR1 (0.37) | PRKDCMAPTNPSR1KDM4ECYP3A4 | |
| SCHEMBL5707975 | 0.93 | MAPT (0.38) | PRKDCMAPTNPSR1KDM4ECYP3A4 | |
| SCHEMBL8845387 | 0.93 | LMNA (0.38) | PRKDCMAPTNPSR1KDM4ECYP3A4 | |
| SCHEMBL12377275 | 0.91 | MAPT (0.39) | PRKDCMAPTNPSR1KDM4ECYP3A4 | |
| SCHEMBL8845473 | 0.91 | MAPT (0.40) | PRKDCMAPTNPSR1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111335051-A | Environment-friendly leather-like velvet photosensitive and photochromic printing paste and preparation method thereof | 广州明诺新材料科技有限公司 | 2020-06-26 | — | — | CN | claimed |
| EP-1410786-B1 | Cosmetic composition comprising at least two dyes whereof at least one is photochromic | OREAL (FR) | 2008-01-02 | — | — | EP | claimed |
| US-20070159594-A9 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2007-07-12 | — | — | US | claimed |
| EP-1410784-B1 | Cosmetic composition comprising an oil phase and a naphthopyran dye and method | OREAL (FR) | 2007-02-07 | — | — | EP | claimed |
| EP-1410785-B1 | Make-up product, combining two compositions, comprising a photochromic dye and a goniochromatic agent, respectively | OREAL (FR) | 2007-01-03 | — | — | EP | claimed |
| EP-0984053-B1 | PHOTOCHROMIC POLYMERIZABLE COMPOSITION | TOKUYAMA CORP (JP) | 2006-09-06 | — | — | EP | claimed |
| US-20050276767-A1 | Composition containing an oily phase and a naphthopyran dye, cosmetic treatment processes | L'OREAL (FR) | 2005-12-15 | — | — | US | claimed |
| US-20050254003-A1 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2005-11-17 | — | — | US | claimed |
| US-20040228817-A1 | Makeup combining at least one photochromic dye and at least one goniochromatic agent | L'OREAL (FR) | 2004-11-18 | — | — | US | claimed |
| US-20040228818-A1 | Cosmetic composition combining at least two dyes including at least one photochromic dye | L'OREAL (FR) | 2004-11-18 | — | — | US | claimed |
| EP-1410784-A1 | Cosmetic composition comprising an oil phase and a naphthopyran dye and method | L'OREAL (FR) | 2004-04-21 | — | — | EP | claimed |
| US-6362248-B1 | MIXTURE OF (METH)ACRYLATE MONOMER AND CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2002-03-26 | — | — | US | claimed |
| WO-1999031081-A1 | PH SENSITIVE PHOTOCHROMIC DYES | JAMES ROBINSON LIMITED (GB) | 1999-06-24 | — | — | WO | claimed |
| US-5623005-A | NAPTHOPYRAN COMPOUNDS CONTAINING AMINE SUBSTITUTION AT 6-POSITION; USEFUL TO MAKE OPHTHALMIC LENS | PILKINGTON PLC (GB) | 1997-04-22 | — | — | US | claimed |
| EP-0691965-B1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1996-12-04 | — | — | EP | claimed |
| EP-0691965-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1996-01-17 | — | — | EP | claimed |
| WO-1994022850-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1994-10-13 | — | — | WO | claimed |
| US-20250345255-A1 | COMPOSITIONS FOR IMPROVING NAIL HEALTH | L'ORÉAL (FR) | 2025-11-13 | — | — | US | disclosed |
| EP-0691965-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022850-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1994-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040228817-A1 | Makeup combining at least one photochromic dye and at least one goniochromatic agent | GYPA, TYR, GLA | PRKDC 831/4885MAPT 3990/4885NPSR1 4195/4885 |
| US-20050276767-A1 | Composition containing an oily phase and a naphthopyran dye, cosmetic treatment processes | CUTA, TYR, TPSD1 | PRKDC 1445/4885MAPT 3880/4885NPSR1 1324/4885 |
| US-20040228818-A1 | Cosmetic composition combining at least two dyes including at least one photochromic dye | CUTA, TYR, LAGE3 | PRKDC 565/4885MAPT 2972/4885NPSR1 4298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.