Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22502433 | 1.00 | L3MBTL1 (0.55) | L3MBTL1CYP19A1RAPGEF4HTR6PKM | |
| SCHEMBL20488209 | 0.87 | L3MBTL1 (0.55) | L3MBTL1CYP19A1RAPGEF4HTR6PKM | |
| SCHEMBL29378984 | 0.83 | L3MBTL1 (0.51) | L3MBTL1CYP19A1RAPGEF4HTR6PKM | |
| SCHEMBL22502398 | 0.83 | L3MBTL1 (0.51) | L3MBTL1CYP19A1RAPGEF4HTR6PKM | |
| SCHEMBL1354366 | 0.83 | L3MBTL1 (0.59) | L3MBTL1CYP19A1RAPGEF4HTR6PKM | |
| SCHEMBL30081932 | 0.83 | L3MBTL1 (0.59) | L3MBTL1CYP19A1RAPGEF4HTR6PKM | |
| SCHEMBL1749163 | 0.83 | L3MBTL1 (0.59) | L3MBTL1CYP19A1RAPGEF4HTR6PKM | |
| SCHEMBL2237896 | 0.82 | L3MBTL1 (0.62) | L3MBTL1CYP19A1RAPGEF4HTR6PKM | |
| SCHEMBL1749202 | 0.82 | L3MBTL1 (0.62) | L3MBTL1CYP19A1RAPGEF4HTR6PKM | |
| SCHEMBL9948819 | 0.81 | HTR6 (0.55) | L3MBTL1CYP19A1HTR6POLBALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947352-A1 | COMPLEMENT MODULATORS AND RELATED METHODS | RA Pharmaceuticals, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |