SCHEMBL29376322

SCHEMBL29376322

C=Cc1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 3/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ ALDH1A1 P00352 6/20 0.44
▸ TP53 P04637 1/20 0.38
▸ KDM4E B2RXH2 3/20 0.37
▸ HPGD P15428 3/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ NFKB1 P19838 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ NFKB2 Q00653 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ RELA Q04206 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ TSHR P16473 1/20 0.36
▸ TYMS P04818 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92283 1.00 TDP1 (0.46) TDP1ALOX15ALDH1A1TP53KDM4E
SCHEMBL21616546 0.89 ALDH1A1 (0.38) TDP1ALOX15ALDH1A1TP53KDM4E
Di(Hydroxyethyl)Ether SCHEMBL27766202 0.84 ALDH1A1 (0.34) TDP1ALOX15ALDH1A1MEN1POLB
SCHEMBL12337781 0.83 TDP1 (0.50) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL12314487 0.83 TDP1 (0.50) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL4547116 0.81 TDP1 (0.48) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL13393166 0.81 MAOA (0.45) TDP1ALOX15ALDH1A1L3MBTL1
SCHEMBL28269539 0.80 TDP1 (0.39) TDP1ALOX15ALDH1A1KDM4EHPGD
Phthalic Anhydride SCHEMBL27920923 0.77 ALDH1A1 (0.61) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL18906447 0.76 CNR2 (0.50) TDP1ALOX15ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637560-B2 Resin composition DUPONT ELECTRONIC MATERIALS INTERNATIONAL, LLC (US) 2026-05-26 — — US disclosed
US-20240317940-A1 PHOTOIMAGABLE DIELECTRICS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-09-26 — — US disclosed
US-20240317985-A1 RESIN COMPOSITION U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-09-26 — — US disclosed
CN-118684886-A Photosensitive media 罗门哈斯电子材料有限公司 2024-09-24 — — CN disclosed
CN-118685032-A Resin composition 罗门哈斯电子材料有限公司 2024-09-24 — — CN disclosed
WO-2024037527-A1 BTK DEGRADING COMPOUNDS BEIJING NEOX BIOTECH LIMITED (CN) 2024-02-22 — — WO disclosed
WO-2022091916-A1 CURABLE COMPOSITION 住友化学株式会社 2022-05-05 — — WO disclosed
WO-2022065357-A1 COLORING COMPOSITION 住友化学株式会社 2022-03-31 — — WO disclosed
WO-2022050051-A1 COMPOUND 住友化学株式会社 2022-03-10 — — WO disclosed
WO-2022044824-A1 LAYERED BODY AND DISPLAY DEVICE 住友化学株式会社 2022-03-03 — — WO disclosed
WO-2022044822-A1 RESIN COMPOSITION, RESIN FILM, AND DISPLAY DEVICE 住友化学株式会社 2022-03-03 — — WO disclosed
WO-2022024743-A1 DISPLAY DEVICE 住友化学株式会社 2022-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637560-B2 Resin composition TAF1, TAF11, TAF5 TDP1 502/4885ALOX15 1213/4885ALDH1A1 1043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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