SCHEMBL4547116

SCHEMBL4547116

O=Cc1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 3/20 0.48
▸ ALOX15 P16050 1/20 0.48
▸ ALDH1A1 P00352 9/20 0.46
▸ CYP2A6 P11509 2/20 0.42
▸ KDM4E B2RXH2 4/20 0.40
▸ PTGS2 P35354 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.39
▸ HPGD P15428 3/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ NFKB2 Q00653 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ RELA Q04206 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12337781 0.84 TDP1 (0.50) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL12314487 0.84 TDP1 (0.50) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL21908190 0.84 ELANE (0.47) TDP1ALOX15ALDH1A1CYP2A6RAB9A
SCHEMBL22419406 0.84 ELANE (0.47) TDP1ALOX15ALDH1A1CYP2A6RAB9A
SCHEMBL92283 0.81 TDP1 (0.46) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL29376322 0.81 TDP1 (0.46) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL22419405 0.80 MAOA (0.46) TDP1ALOX15ALDH1A1CYP2A6KDM4E
SCHEMBL10779728 0.78 MAOA (0.51) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL18906447 0.78 CNR2 (0.50) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL15120734 0.78 CNR2 (0.50) TDP1ALOX15ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290686-A Reinforced polyurethane hard foam material and preparation method thereof 江苏雅克科技股份有限公司 2024-07-05 — — CN disclosed
US-20230203239-A1 Cyclic ether-anhydride photopolyaddition and uses thereof UNIVERSITÉ DE HAUTE-ALSACE (FR) 2023-06-29 — — US disclosed
US-20230203353-A1 ADHESIVE FOR ENDOSCOPE AND CURED PRODUCT THEREOF, AND ENDOSCOPE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2023-06-29 — — US disclosed
WO-2021132865-A1 POLYMER RESIN COMPOUND, METHOD FOR PRODUCING SAME, AND PHOTOSENSITIVE RESIN COMPOSITION COMPRISING SAME 주식회사 엘지화학 2021-07-01 — — WO disclosed
WO-2020043453-A1 PIGMENT DISPERSANT BASF COATINGS GMBH (DE) 2020-03-05 — — WO disclosed
US-20170071699-A1 Plastic Container for Containing Dental Adhesive Composition TOKUYAMA DENTAL CORPORATION (JP) 2017-03-16 — — US disclosed
US-9541795-B2 Liquid crystal display device and method for manufacturing the same SONY CORPORATION (JP) 2017-01-10 — — US disclosed
US-9523889-B2 Liquid crystal display unit and method of manufacturing the same SONY CORPORATION (JP) 2016-12-20 — — US disclosed
EP-2450348-B1 NOVEL DIARYLAMINE COMPOUND, AND ANTI-AGING AGENT, POLYMER COMPOSITION, CROSSLINKED RUBBER PRODUCT AND MOLDED ARTICLE THEREOF, AND METHOD FOR PRODUCING DIARYLAMINE COMPOUND ZEON CORP (JP) 2016-12-14 — — EP disclosed
US-9507210-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2016-11-29 — — US disclosed
US-20140071390-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2014-03-13 — — US disclosed
US-20130155360-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2013-06-20 — — US disclosed
US-20130095426-A1 PHOTOSENSITIVE POLYMIDES ETERNAL CHEMICAL CO., LTD. (TW) 2013-04-18 — — US disclosed
EP-2450348-A1 NOVEL DIARYLAMINE COMPOUND, AND ANTI-AGING AGENT, POLYMER COMPOSITION, CROSSLINKED RUBBER PRODUCT AND MOLDED ARTICLE THEREOF, AND METHOD FOR PRODUCING DIARYLAMINE COMPOUND Zeon Corporation (JP) 2012-05-09 — — EP disclosed
WO-2008097065-A1 ALKALI-DEVELOPABLE RESINS, METHOD FOR PREPARING THE SAME AND PHOTOSENSITIVE COMPOSITION COMPRISING THE ALKALI-DEVELOPABLE RESINS LG CHEM, LTD. (KR) 2008-08-14 — — WO disclosed
US-7193030-B2 Acid anhydride and polyimide using the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-03-20 — — US disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 — — US disclosed
US-6084106-A Adhesion promoters and methods of their synthesis and use THIOKOL CORPORATION (US) 2000-07-04 — — US disclosed
US-6072055-A Adhesion promoters and methods of their synthesis and use CORDANT TECHNOLOGIES INC. (US) 2000-06-06 — — US disclosed
EP-0355435-A2 Polycarbonate composition GENERAL ELECTRIC COMPANY (US) 1990-02-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 TDP1 3063/4885ALOX15 1802/4885ALDH1A1 1488/4885
US-20170071699-A1 Plastic Container for Containing Dental Adhesive Composition CCDC47, PSMD7, PSD TDP1 2314/4885ALOX15 2082/4885ALDH1A1 3449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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