SCHEMBL92283

SCHEMBL92283

C=Cc1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 3/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ ALDH1A1 P00352 6/20 0.44
▸ TP53 P04637 1/20 0.38
▸ KDM4E B2RXH2 3/20 0.37
▸ HPGD P15428 3/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ NFKB1 P19838 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ NFKB2 Q00653 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ RELA Q04206 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ TSHR P16473 1/20 0.36
▸ TYMS P04818 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376322 1.00 TDP1 (0.46) TDP1ALOX15ALDH1A1TP53KDM4E
SCHEMBL21616546 0.89 ALDH1A1 (0.38) TDP1ALOX15ALDH1A1TP53KDM4E
Di(Hydroxyethyl)Ether SCHEMBL27766202 0.84 ALDH1A1 (0.34) TDP1ALOX15ALDH1A1MEN1POLB
SCHEMBL12337781 0.83 TDP1 (0.50) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL12314487 0.83 TDP1 (0.50) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL4547116 0.81 TDP1 (0.48) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL13393166 0.81 MAOA (0.45) TDP1ALOX15ALDH1A1L3MBTL1
SCHEMBL28269539 0.80 TDP1 (0.39) TDP1ALOX15ALDH1A1KDM4EHPGD
Phthalic Anhydride SCHEMBL27920923 0.77 ALDH1A1 (0.61) TDP1ALOX15ALDH1A1KDM4EHPGD
SCHEMBL18906447 0.76 CNR2 (0.50) TDP1ALOX15ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1091 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118812777-A Anhydride-containing sulfonyl/phosphonyl copolymer and preparation method and application thereof 四川大学 2024-10-22 — — CN claimed
WO-2024095573-A1 POLYIMIDE PRECURSOR AND RESIN COMPOSITION HDマイクロシステムズ株式会社 2024-05-10 — — WO claimed
EP-3720597-B1 MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES STICHTING TECHNISCHE WETENSCHAPPEN (NL) 2023-11-29 — — EP claimed
US-11612877-B2 Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2023-03-28 — — US claimed
US-20200368721-A1 Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2020-11-26 — — US claimed
CN-106883558-A Packaging of photoelectric device composition 苏州市汇涌进光电有限公司 2017-06-23 — — CN claimed
US-6852367-B2 A curable B-staged organo polysilsesquioxanes free of the alcohol of reaction and stabilized by an organic acid for longer shelf life; forming a dielectric film by curing and removing an included pore-forming material SHIPLEY COMPANY, L.L.C. (US) 2005-02-08 — — US claimed
US-5741585-A Polyamic acid precursors and methods for preparing higher molecular weight polyamic acids and polyimidebenzoxazole THE DOW CHEMICAL COMPANY (US) 1998-04-21 — — US claimed
EP-0400746-B1 Cross-linkable compositions based on polyphenylene ethers and unsaturated monomers copolymerizable radically ENICHEM SPA (IT) 1994-06-22 — — EP claimed
US-5171761-A Excellent dimensional stability, creep resistance, excellent adhesion to metal supports ENICHEM S.P.A. (IT) 1992-12-15 — — US claimed
US-5159014-A Flexibility, low temperature and oil resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-10-27 — — US claimed
US-4497935-A RUBBER-MODIFIED MAIC ACID PREPOLYMER THE UNITES STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1985-02-05 — — US claimed
US-4389504-A AROMATIC AMINE CAPPED ACRYLONITRILE-BUTADIENE COPOLYMER OR SILICONE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION OFFICE OF GENERAL COUNSEL-CODE GP (US) 1983-06-21 — — US claimed
JP-60260624-A — — None — — JP disclosed
US-12613465-B2 Photosensitive resin composition and method for producing cured relief pattern ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-04-28 — — US disclosed
US-12552888-B2 Curable resin composition and display device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-02-17 — — US disclosed
EP-0071372-A1 Isoimide containing oligomers Hughes Aircraft Company (US) 1983-02-09 — — EP disclosed
US-4302336-A A CROSSLINKED AMINE-MODIFIED ACRYLIC POLYMER; DESALTING OF BRINES BY REVERSE OSMOSIS TEIJIN LIMITED (JP) 1981-11-24 — — US disclosed
EP-0008945-A2 Semipermeable composite membrane, process for producing said membrane, and method of desalination using said membrane TEIJIN LIMITED (JP) 1980-03-19 — — EP disclosed
US-4028482-A LOW VISCOSITY POLYALKENAMER SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-06-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12613465-B2 Photosensitive resin composition and method for producing cured relief pattern ARCN1, GLRA1, PSMA1 TDP1 2890/4885ALOX15 2472/4885ALDH1A1 3316/4885
US-12552888-B2 Curable resin composition and display device RAD51, LPO, FTO TDP1 1957/4885ALOX15 552/4885ALDH1A1 1278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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