Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824030 | 0.81 | RAB9A (0.62) | NPC1MEN1KMT2AHSP90AA1SLC2A1 | |
| SCHEMBL2592673 | 0.80 | HSP90AA1 (0.46) | NPC1MEN1KMT2AHSP90AA1SLC2A1 | |
| SCHEMBL18588878 | 0.79 | MAPT (0.53) | NPC1MEN1KMT2AHSP90AA1SLC2A1 | |
| Nifurthiazole SCHEMBL194337 | 0.78 | HSP90AA1 (0.45) | NPC1MEN1KMT2AHSP90AA1SLC2A1 | |
| SCHEMBL3344653 | 0.76 | MAPT (0.53) | NPC1MEN1KMT2AHSP90AA1SLC2A1 | |
| SCHEMBL11827105 | 0.73 | NPC1 (0.49) | NPC1MEN1KMT2AHSP90AA1SLC2A1 | |
| SCHEMBL11827112 | 0.73 | NPC1 (0.49) | NPC1MEN1KMT2AHSP90AA1SLC2A1 | |
| SCHEMBL5901944 | 0.68 | SLC2A1 (0.42) | NPC1MEN1KMT2AHSP90AA1SLC2A1 | |
| SCHEMBL11610175 | 0.64 | CHEK1 (0.43) | NPC1MEN1KMT2ASLC2A1MAPT | |
| SCHEMBL21823820 | 0.63 | CYP19A1 (0.56) | NPC1MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118594693-B | Vertical roller mill with main roller and auxiliary roller as active rotating parts and design method thereof | 合肥中亚建材装备有限责任公司天津分公司 | 2026-05-19 | — | — | CN | claimed |
| CN-119783275-A | Design method for ball screw pair surface parameters working under extreme temperature working condition | 南京理工大学 | 2025-04-08 | — | — | CN | claimed |
| CN-118594693-A | Vertical roller mill with main roller and auxiliary roller as active rotating parts and design method thereof | 中材（天津）粉体技术装备有限公司 | 2024-09-06 | — | — | CN | claimed |
| CN-118058281-A | Application of DMNT in preventing and controlling liriomyza sativae | 浙江大学海南研究院 | 2024-05-24 | — | — | CN | claimed |
| CN-118594693-B | Vertical roller mill with main roller and auxiliary roller as active rotating parts and design method thereof | 合肥中亚建材装备有限责任公司天津分公司 | 2026-05-19 | — | — | CN | disclosed |
| EP-4637738-A2 | INHIBITORS OF JAK2 | Llydaw Therapeutics, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| CN-114015726-B | Delivery, use and therapeutic application of CRISPR-CAS systems and compositions for targeting disorders and diseases with viral components | 布罗德研究所有限公司 | 2025-06-24 | — | — | CN | disclosed |
| WO-2025103829-A1 | SYSTEM AND METHOD FOR ASSESSING AND OPTIMIZING WIND FARMS USING MACHINE LEARNING | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2025-05-22 | — | — | WO | disclosed |
| CN-113425857-B | Delivery and use of CRISPR-CAS systems, vectors and compositions for liver targeting and treatment | 布罗德研究所有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-119783275-A | Design method for ball screw pair surface parameters working under extreme temperature working condition | 南京理工大学 | 2025-04-08 | — | — | CN | disclosed |
| US-20250111889-A1 | DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES | UNIVERSITY OF WASHINGTON | 2025-04-03 | — | — | US | disclosed |
| US-20250101468-A1 | DELIVERY AND USE OF THE CRISPR-CAS SYSTEMS, VECTORS AND COMPOSITIONS FOR HEPATIC TARGETING AND THERAPY | THE BROAD INSTITUTE, INC. (US) | 2025-03-27 | — | — | US | disclosed |
| CN-118594693-A | Vertical roller mill with main roller and auxiliary roller as active rotating parts and design method thereof | 中材（天津）粉体技术装备有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-112596890-B | Flight program operation logic structuring method and system | 中国商用飞机有限责任公司北京民用飞机技术研究中心 | 2024-07-23 | — | — | CN | disclosed |
| CN-116144681-B | Tomato leaf miner Dnmt1 gene and its function in stress temperature response and development of tomato leaf miner | 中国农业科学院植物保护研究所 | 2024-07-09 | — | — | CN | disclosed |
| US-12018275-B2 | Delivery and use of the CRISPR-CAS systems, vectors and compositions for hepatic targeting and therapy | THE BROAD INSTITUTE, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| CN-113671080-B | Method for improving tea tree to avoid adults of tea geometrid | 安徽农业大学 | 2023-06-02 | — | — | CN | disclosed |
| US-11572384-B2 | Unusual substrates of tubulin tyrosine ligase | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2023-02-07 | — | — | US | disclosed |
| CN-109657112-B | Cross-modal Hash learning method based on anchor point diagram | 九江学院 | 2022-07-08 | — | — | CN | disclosed |
| CN-114015726-A | Delivery, use and therapeutic applications of CRISPR-CAS systems and compositions for targeting disorders and diseases with viral components | 布罗德研究所有限公司 | 2022-02-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572384-B2 | Unusual substrates of tubulin tyrosine ligase | TTL, TUBA1C, TUBB6 | NPC1 3969/4885MEN1 3206/4885KMT2A 3093/4885 |
| US-20250111889-A1 | DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES | DHFR, CCNH, ODC1 | NPC1 2613/4885MEN1 2382/4885KMT2A 896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.