Phenylalanine

Phenylalanine

SCHEMBL293835

CC(C)C[C@H](N)C(=O)OC(=O)[C@@H](N)Cc1c[nH]c2ccccc12.CSCC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)OC[C@H](N)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
MPO P05164 1/20 0.44
MAPT P10636 1/20 0.44
TSHR P16473 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
HIF1A Q16665 1/20 0.44
CTSC P53634 2/20 0.42
TACR1 P25103 2/20 0.39
ERAP2 Q6P179 6/20 0.39
ERAP1 Q9NZ08 6/20 0.39
LNPEP Q9UIQ6 1/20 0.39
CCKBR P32239 3/20 0.38
ECE1 P42892 1/20 0.38
TP53 P04637 1/20 0.38
MDM2 Q00987 1/20 0.38
HSP90AA1 P07900 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL9903590 0.96 MEN1 (0.48) MEN1KMT2AKDM4ELMNAMPO
Tryptophan SCHEMBL293836 0.86 MEN1 (0.49) MEN1KMT2AKDM4ELMNAMPO
SCHEMBL3442895 0.85 KDM4E (0.57) MEN1KMT2AKDM4ELMNAMPO
Tryptophan SCHEMBL9903583 0.83 MEN1 (0.55) MEN1KMT2AKDM4ELMNAMPO
Tryptophan SCHEMBL4291975 0.83 MEN1 (0.57) MEN1KMT2AKDM4ELMNAMPO
Tryptophan SCHEMBL9903592 0.82 MEN1 (0.53) MEN1KMT2AKDM4ELMNAMPO
Tryptophan SCHEMBL294283 0.80 MEN1 (0.52) MEN1KMT2AKDM4ELMNAMPO
D-Tryptophan SCHEMBL2221762 0.80 MEN1 (0.53) MEN1KMT2AKDM4ELMNAMPO
D-Tryptophan SCHEMBL2221757 0.80 KMT2A (0.57) MEN1KMT2AKDM4ELMNAMPO
Tryptophan SCHEMBL295705 0.80 KDM4E (0.43) MEN1KMT2AKDM4ELMNAMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463378-B1 Alpha isomaltosylglucosaccharide synthase, process for producing the same and use thereof HAYASHIBARA CO (JP) 2015-12-23 EP disclosed
EP-1229112-B1 ALPHA-ISOMALTOSYLGLUCOSACCHARIDE SYNTHASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF HAYASHIBARA BIOCHEM LAB (JP) 2012-03-14 EP disclosed
EP-1445325-B1 PROCESSES FOR PRODUCING ISOMALTOSE AND ISOMALTITOL AND USE THEREOF HAYASHIBARA BIOCHEM LAB (JP) 2010-05-26 EP disclosed
EP-1360988-B1 METHOD FOR DEHYDRATING MOIST ARTICLE USING A CYCLOTETRASACCHARIDE HAYASHIBARA BIOCHEM LAB (JP) 2006-10-11 EP disclosed
EP-1445325-A1 PROCESSES FOR PRODUCING ISOMALTOSE AND ISOMALTITOL AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2004-08-11 EP disclosed
EP-1360988-A1 DEHYDRATING AGENT AND METHOD FOR DEHYDRATING MOIST ARTICLE USING THE AGENT AND DEHYDRATED ARTICLE OBTAINED BY THE METHOD Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2003-11-12 EP disclosed
EP-1229112-A1 ALPHA-ISOMALTOSYLGLUCOSACCHARIDE SYNTHASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2002-08-07 EP disclosed