SCHEMBL2938397

SCHEMBL2938397

Cc1ccc2c(c1)C(CO)c1c(CC(C)C)cccc1-2

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
GFER P55789 1/20 0.33
KMT2A Q03164 1/20 0.33
ELANE P08246 3/20 0.33
CTSG P08311 1/20 0.33
SLC5A1 P13866 1/20 0.30
SLC5A2 P31639 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9449382 0.74 TRPM5 (0.37) MEN1ALDH1A1HPGDKMT2AELANE
SCHEMBL9449414 0.74 HRH3 (0.46) MEN1ALDH1A1LMNAHPGDKMT2A
SCHEMBL2938396 0.68 LDHA (0.32) ALDH1A1HPGDKMT2ASLC5A1SLC5A2
SCHEMBL12704857 0.67 PPIA (0.44) MEN1ALDH1A1LMNAHPGDKMT2A
SCHEMBL2936143 0.67 GABRA1 (0.44) GABRA1GABRB2MEN1ALDH1A1LMNA
SCHEMBL2230423 0.67 HTR2A (0.42) MEN1ALDH1A1HPGDKMT2A
SCHEMBL31274740 0.67 HTR2A (0.42) MEN1ALDH1A1HPGDKMT2A
SCHEMBL14327287 0.66 ALDH1A1 (0.36) ALDH1A1HPGD
SCHEMBL14396288 0.66 MAP2K4 (0.35) ALDH1A1
SCHEMBL6912097 0.65 PDK2 (0.39) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1411067-B1 POLYMER HAVING UNIQUE OPTICAL PROPERTY JAPAN SCIENCE & TECH AGENCY (JP) 2010-09-22 EP disclosed
US-7323538-B2 Polymer having unique optical property and polymerizable monomer therefor JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-01-29 US disclosed
US-20040132963-A1 Polymer having unique optical property and polymerizable monomer therefor JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2004-07-08 US disclosed
EP-1411067-A1 POLYMER HAVING UNIQUE OPTICAL PROPERTY AND POLYMERIZABLE MONOMER THEREFOR Japan Science and Technology Corporation (JP) 2004-04-21 EP disclosed