Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15578345 | 1.00 | L3MBTL1 (0.62) | L3MBTL1RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL15578359 | 0.86 | L3MBTL1 (0.57) | L3MBTL1RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL16933469 | 0.83 | L3MBTL1 (0.58) | L3MBTL1RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL15578406 | 0.80 | MLYCD (0.53) | L3MBTL1RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL12201868 | 0.78 | L3MBTL1 (0.62) | L3MBTL1RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL3936634 | 0.76 | AKR1C3 (0.51) | L3MBTL1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL29387446 | 0.75 | L3MBTL1 (0.48) | L3MBTL1RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL16933575 | 0.75 | L3MBTL1 (0.48) | L3MBTL1RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL15577951 | 0.74 | F10 (0.49) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL29386858 | 0.74 | HDAC8 (0.51) | RAB9AALDH1A1TSHRHTTF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114533729-A | Glucosylceramide synthase inhibitors | 建新公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108864076-B | Glucosylceramide synthase inhibitors | 建新公司 | 2022-02-11 | — | — | CN | disclosed |