Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16933575 | 1.00 | L3MBTL1 (0.48) | L3MBTL1RAB9ANR1H2NR1H3ALDH1A1 | |
| SCHEMBL15577911 | 0.94 | L3MBTL1 (0.47) | L3MBTL1RAB9AALDH1A1NTMT1 | |
| SCHEMBL15578271 | 0.85 | ALDH1A1 (0.42) | ALDH1A1NSD2LMNANTMT1 | |
| SCHEMBL16933485 | 0.85 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KMT2AEPHX2LMNA | |
| SCHEMBL29384728 | 0.85 | ALDH1A1 (0.42) | ALDH1A1NSD2LMNANTMT1 | |
| SCHEMBL16933663 | 0.84 | ALDH1A1 (0.41) | ALDH1A1NSD2LMNAMAPTNTMT1 | |
| SCHEMBL29387286 | 0.84 | ALDH1A1 (0.41) | ALDH1A1NSD2LMNAMAPTNTMT1 | |
| SCHEMBL16933468 | 0.81 | NTMT1 (0.44) | ALDH1A1EPHX2LMNANTMT1 | |
| SCHEMBL16933469 | 0.81 | L3MBTL1 (0.58) | L3MBTL1RAB9ANR1H2NR1H3ALDH1A1 | |
| SCHEMBL15578307 | 0.78 | RAB9A (0.46) | L3MBTL1RAB9ANR1H2NR1H3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114533729-A | Glucosylceramide synthase inhibitors | 建新公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108864076-B | Glucosylceramide synthase inhibitors | 建新公司 | 2022-02-11 | — | — | CN | disclosed |