Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | F10 | P00742 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15578345 | 0.83 | L3MBTL1 (0.62) | L3MBTL1RAB9AF10ALDH1A1TSHR | |
| SCHEMBL29384777 | 0.83 | L3MBTL1 (0.62) | L3MBTL1RAB9AF10ALDH1A1TSHR | |
| SCHEMBL16933440 | 0.81 | HPGD (0.51) | L3MBTL1RAB9AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL29387446 | 0.81 | L3MBTL1 (0.48) | L3MBTL1RAB9AF10ALDH1A1TSHR | |
| SCHEMBL16933575 | 0.81 | L3MBTL1 (0.48) | L3MBTL1RAB9AF10ALDH1A1TSHR | |
| SCHEMBL15577911 | 0.80 | L3MBTL1 (0.47) | L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL15578307 | 0.79 | RAB9A (0.46) | L3MBTL1RAB9AF10ALDH1A1TSHR | |
| SCHEMBL15578152 | 0.79 | L3MBTL1 (0.46) | L3MBTL1RAB9AF10ALDH1A1TSHR | |
| SCHEMBL15578359 | 0.78 | L3MBTL1 (0.57) | L3MBTL1RAB9AF10ALDH1A1TSHR | |
| SCHEMBL16933418 | 0.75 | MLYCD (0.52) | RAB9AALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008316-B2 | Glucosylceramide synthase inhibitors | GENZYME CORPORATION (US) | 2021-05-18 | — | — | US | disclosed |
| US-20180065957-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2018-03-08 | — | — | US | disclosed |
| US-20150210681-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2015-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210681-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GBA1, GBA2, GAA | L3MBTL1 1688/4885RAB9A 699/4885F10 3367/4885 |
| US-20180065957-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GBA1, GBA2, GAA | L3MBTL1 1688/4885RAB9A 699/4885F10 3367/4885 |
| US-11008316-B2 | Glucosylceramide synthase inhibitors | GBA1, GBA2, GAA | L3MBTL1 2336/4885RAB9A 641/4885F10 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.