Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.43 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL2938480 | 0.94 | LMNA (0.56) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Glycerin SCHEMBL4630792 | 0.90 | LMNA (0.60) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Cadaverine Tartrate SCHEMBL3039384 | 0.88 | LMNA (0.50) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Cadaverine Tartrate SCHEMBL2031625 | 0.88 | LMNA (0.50) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Oxalic Acid SCHEMBL27842531 | 0.85 | LMNA (0.53) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Glycerin SCHEMBL967740 | 0.85 | LMNA (0.53) | LMNAALDH1A1OR51E2SLC22A16THRB | |
| Glycerin SCHEMBL5030995 | 0.84 | LMNA (0.60) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Glycerin SCHEMBL6009743 | 0.84 | LMNA (0.60) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Glycerin SCHEMBL9509912 | 0.84 | LMNA (0.60) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Glycerin SCHEMBL27520568 | 0.84 | LMNA (0.60) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358654-B | Method for preparing high-activity adsorption ceramsite by using low-grade diatomite | 武汉理工大学 | 2021-05-18 | — | — | CN | disclosed |