Platyphylloside

Platyphylloside

SCHEMBL29386138

O=C(CCc1ccc(O)cc1)C[C@H](CCc1ccc(O)cc1)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 4/20 0.69
▸ PPARD Q03181 4/20 0.69
▸ PPARA Q07869 4/20 0.69
▸ SYNJ2 O15056 2/20 0.67
▸ KDM4E B2RXH2 2/20 0.67
▸ MAPT P10636 2/20 0.67
▸ ABL1 P00519 1/20 0.67
▸ ALPL P05186 1/20 0.67
▸ POLB P06746 1/20 0.67
▸ ALPI P09923 1/20 0.67
▸ GAA P10253 1/20 0.67
▸ ALPG P10696 1/20 0.67
▸ PABPC1 P11940 1/20 0.67
▸ RECQL P46063 1/20 0.67
▸ GALK1 P51570 1/20 0.67
▸ CASP7 P55210 1/20 0.67
▸ CASP6 P55212 1/20 0.67
▸ MCL1 Q07820 1/20 0.67
▸ RIN1 Q13671 1/20 0.67
▸ EIF4H Q15056 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24993777 0.82 PRKCA (0.51) PPARGPPARDPPARASYNJ2KDM4E
SCHEMBL15773392 0.80 SYNJ2 (1.00) PPARGPPARDPPARASYNJ2KDM4E
SCHEMBL17157084 0.80 SYNJ2 (1.00) PPARGPPARDPPARASYNJ2KDM4E
SCHEMBL5320094 0.78 TYR (0.71) PPARGPPARDPPARASYNJ2KDM4E
SCHEMBL16234564 0.78 TYR (0.71) PPARGPPARDPPARASYNJ2KDM4E
SCHEMBL28971367 0.78 TYR (0.71) PPARGPPARDPPARASYNJ2KDM4E
SCHEMBL329049 0.78 TYR (0.71) PPARGPPARDPPARASYNJ2KDM4E
SCHEMBL16233068 0.78 TYR (0.71) PPARGPPARDPPARASYNJ2KDM4E
Alnuside B SCHEMBL22796510 0.75 PPARG (0.49) PPARGPPARDPPARASYNJ2KDM4E
Alnuside B SCHEMBL12672476 0.75 PPARG (0.49) PPARGPPARDPPARASYNJ2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4267103-A1 PLANT EXTRACTS FOR IMPROVING SKIN BARRIER FUNCTION Oriflame Cosmetics AG (CH) 2023-11-01 — — EP claimed
US-20230270805-A1 A COMPOSITION COMPRISING AN EXTRACT OF ALDER TREE OR THE ISOLATED COMPOUNDS THEREFROM FOR TREATING AND PREVENTING SKELETON MUSCLE-RELATED DISORDER AND THE USE THEREOF SOOKMYUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2023-08-31 — — US claimed
WO-2022135827-A1 PLANT EXTRACTS FOR IMPROVING SKIN BARRIER FUNCTION ORIFLAME COSMETICS AG (CH) 2022-06-30 — — WO claimed
WO-2022035115-A1 COMPOSITION FOR PREVENTION AND TREATMENT OF SKELETAL MUSCLE-RELATED DISEASES CONTAINING ALNUS JAPONICA EXTRACT OR COMPOUND ISOLATED THEREFROM AND USE THEREOF 숙명여자대학교 산학협력단 2022-02-17 — — WO claimed
US-20250073156-A1 Topical Compositions and Methods to Promote Optimal Dermal White Adipose Tissue Composition in Vivo GALANIN IVAN (US) 2025-03-06 — — US disclosed
US-12226517-B2 Topical compositions and methods to promote optimal dermal white adipose tissue composition in vivo GALANIN IVAN (US) 2025-02-18 — — US disclosed
EP-4267103-A1 PLANT EXTRACTS FOR IMPROVING SKIN BARRIER FUNCTION Oriflame Cosmetics AG (CH) 2023-11-01 — — EP disclosed
CN-116685341-A Plant extracts for improving skin barrier function 欧瑞莲化妆品股份有限公司 2023-09-01 — — CN disclosed
US-20230270805-A1 A COMPOSITION COMPRISING AN EXTRACT OF ALDER TREE OR THE ISOLATED COMPOUNDS THEREFROM FOR TREATING AND PREVENTING SKELETON MUSCLE-RELATED DISORDER AND THE USE THEREOF SOOKMYUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2023-08-31 — — US disclosed
WO-2022135827-A1 PLANT EXTRACTS FOR IMPROVING SKIN BARRIER FUNCTION ORIFLAME COSMETICS AG (CH) 2022-06-30 — — WO disclosed
WO-2022035115-A1 COMPOSITION FOR PREVENTION AND TREATMENT OF SKELETAL MUSCLE-RELATED DISEASES CONTAINING ALNUS JAPONICA EXTRACT OR COMPOUND ISOLATED THEREFROM AND USE THEREOF 숙명여자대학교 산학협력단 2022-02-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270805-A1 A COMPOSITION COMPRISING AN EXTRACT OF ALDER TREE OR THE ISOLATED COMPOUNDS THEREFROM FOR TREATING AND PREVENTING SKELETON MUSCLE-RELATED DISORDER AND THE USE THEREOF MAPK6, MAPK13, PYGM PPARG 1297/4885PPARD 1500/4885PPARA 1295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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