Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYNJ2 | O15056 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | ABL1 | P00519 | 1/20 | 1.00 |
| ▸ | ALPL | P05186 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | ALPI | P09923 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | ALPG | P10696 | 1/20 | 1.00 |
| ▸ | PABPC1 | P11940 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | GALK1 | P51570 | 1/20 | 1.00 |
| ▸ | CASP7 | P55210 | 1/20 | 1.00 |
| ▸ | CASP6 | P55212 | 1/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 1/20 | 1.00 |
| ▸ | RIN1 | Q13671 | 1/20 | 1.00 |
| ▸ | EIF4H | Q15056 | 1/20 | 1.00 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15773392 | 1.00 | SYNJ2 (1.00) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL16167402 | 0.81 | SYNJ2 (0.67) | SYNJ2KDM4EABL1ALPLPOLB | |
| Platyphylloside SCHEMBL29386138 | 0.80 | PPARG (0.69) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL29711373 | 0.80 | SYNJ2 (0.65) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL28912294 | 0.76 | SYNJ2 (0.62) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL18803979 | 0.76 | SYNJ2 (0.61) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL3636324 | 0.75 | SYNJ2 (0.59) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL18803975 | 0.74 | SYNJ2 (0.59) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL28565109 | 0.74 | SYNJ2 (0.59) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL28544286 | 0.74 | SYNJ2 (0.59) | SYNJ2KDM4EABL1ALPLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170165285-A1 | METHODS OF PREVENTING TUMOR METASTASIS, TREATING AND PROGNOSING CANCER AND IDENTIFYING AGENTS WHICH ARE PUTATIVE METASTASIS INHIBITORS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-06-15 | — | — | US | disclosed |
| US-20170042857-A1 | SYNAPTOJANIN-2 INHIBITORS FOR USE IN THE TREATMENT OF CANCER | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-02-16 | — | — | US | disclosed |
| US-20150290233-A1 | METHODS OF PREVENTING TUMOR METASTASIS, TREATING AND PROGNOSING CANCER AND IDENTIFYING AGENTS WHICH ARE PUTATIVE METASTASIS INHIBITORS | YEDA RESEARCH AND DEVELOPMENT CO.LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150290233-A1 | METHODS OF PREVENTING TUMOR METASTASIS, TREATING AND PROGNOSING CANCER AND IDENTIFYING AGENTS WHICH ARE PUTATIVE METASTASIS INHIBITORS | SYNJ2, SYNGR2, SNAP29 | SYNJ2 1/4885KDM4E 4477/4885ABL1 3876/4885 |
| US-20170042857-A1 | SYNAPTOJANIN-2 INHIBITORS FOR USE IN THE TREATMENT OF CANCER | SNAP29, SYNJ1, TPX2 | SYNJ2 6/4885KDM4E 1521/4885ABL1 3169/4885 |
| US-20170165285-A1 | METHODS OF PREVENTING TUMOR METASTASIS, TREATING AND PROGNOSING CANCER AND IDENTIFYING AGENTS WHICH ARE PUTATIVE METASTASIS INHIBITORS | SYNJ2, SYNGR2, SNAP29 | SYNJ2 1/4885KDM4E 4477/4885ABL1 3876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.