Zenidolol

Zenidolol

SCHEMBL29387637

Cc1ccc(OC[C@H](O)[C@@H](C)NC(C)C)c2c1CCC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 7/20 1.00
ADRB1 P08588 5/20 1.00
ADRB3 P13945 3/20 1.00
CYP2D6 P10635 2/20 1.00
TSHR P16473 2/20 1.00
KDM4E B2RXH2 2/20 1.00
ADRA2A P08913 1/20 1.00
TP53 P04637 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP3A4 P08684 1/20 1.00
NFKB1 P19838 1/20 1.00
HIF1A Q16665 1/20 1.00
NPSR1 Q6W5P4 2/20 0.97
MEN1 O00255 1/20 0.97
LMNA P02545 1/20 0.97
PMP22 Q01453 1/20 0.97
KMT2A Q03164 1/20 0.97
RXRG P48443 7/20 0.44
RXRA P19793 6/20 0.44
RXRB P28702 6/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zenidolol SCHEMBL146178 1.00 ADRB2 (1.00) ADRB2ADRB1ADRB3CYP2D6TSHR
Zenidolol SCHEMBL29558331 1.00 ADRB2 (1.00) ADRB2ADRB1ADRB3CYP2D6TSHR
Zenidolol SCHEMBL8027938 1.00 ADRB2 (1.00) ADRB2ADRB1ADRB3CYP2D6TSHR
Zenidolol SCHEMBL14941581 1.00 ADRB2 (1.00) ADRB2ADRB1ADRB3CYP2D6TSHR
Zenidolol SCHEMBL15058356 1.00 ADRB2 (1.00) ADRB2ADRB1ADRB3CYP2D6TSHR
Zenidolol SCHEMBL5485188 0.99 ADRB2 (1.00) ADRB2ADRB1ADRB3CYP2D6TSHR
Zenidolol SCHEMBL29686378 0.99 ADRB2 (1.00) ADRB2ADRB1ADRB3CYP2D6TSHR
Zenidolol SCHEMBL31074300 0.99 ADRB2 (1.00) ADRB2ADRB1ADRB3CYP2D6TSHR
SCHEMBL15549338 0.85 ADRB2 (0.74) ADRB2ADRB1ADRB3CYP2D6TSHR
SCHEMBL11266032 0.85 ADRB2 (0.74) ADRB2ADRB1ADRB3CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11246873-B2 Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate THE SCRIPPS RESEARCH INSTITUTE (US) 2022-02-15 US disclosed