Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 12/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimetipirium SCHEMBL2733698 | 0.99 | CHRM2 (0.58) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| Etipirium SCHEMBL29388403 | 0.78 | CHRM2 (0.69) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| Etipirium SCHEMBL916033 | 0.77 | CHRM2 (0.67) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| SCHEMBL5158545 | 0.74 | MEN1 (0.68) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| SCHEMBL29925238 | 0.72 | CHRM3 (0.60) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| SCHEMBL5161453 | 0.71 | MEN1 (0.64) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| Poldine SCHEMBL1641786 | 0.70 | CHRM2 (0.55) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| SCHEMBL2763579 | 0.70 | POLB (0.62) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| Metocinium SCHEMBL2108327 | 0.70 | CHRM2 (0.74) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| SCHEMBL8134339 | 0.70 | CHRM1 (0.71) | CHRM2CHRM3CHRM1CYP2D6CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |